Description
Januvia (Sitagliptin) Coated Tablets 100 mg. №28
Ingredients:
Each coated tablet contains 100 mg of sitagliptin.
Mechanism of Action:
Januvia (sitagliptin) is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by inhibiting the DPP-4 enzyme, which leads to prolonged action of incretin hormones. This action stimulates insulin release and inhibits glucagon secretion, resulting in improved glycemic control.
Pharmacological Properties:
Sitagliptin effectively lowers blood sugar levels by targeting the DPP-4 enzyme and modulating incretin hormone activity.
Indications for Use:
Januvia is indicated for the treatment of type 2 diabetes mellitus in adults to improve glycemic control.
Contraindications:
Do not use Januvia if you have a history of a serious hypersensitivity reaction to sitagliptin. It is contraindicated in patients with type 1 diabetes or diabetic ketoacidosis.
Side Effects:
Common side effects of Januvia may include upper respiratory tract infections, headache, and nasopharyngitis.
Usage Instructions:
The recommended dosage is one 100 mg tablet taken orally once daily. Januvia can be taken with or without food as directed by a healthcare provider.
Benefits Compared to Analogues:
Januvia has demonstrated efficacy in improving glycemic control and reducing HbA1c levels in patients with type 2 diabetes. Comparative studies have shown similar or superior outcomes compared to other oral antidiabetic agents.
Suitable Patient Groups:
Januvia is suitable for adult patients with type 2 diabetes. It is important to monitor renal function in patients taking Januvia, as it is primarily excreted through the kidneys.
Storage Conditions and Shelf Life:
Store Januvia in a cool, dry place away from moisture and heat. Keep the tablets in their original packaging to protect from light. Check the expiration date on the packaging before use.
Packaging Description:
Januvia is available in blister packs containing 28 coated tablets of 100 mg each.
Clinical Evidence and Proven Effectiveness:
Studies have shown that sitagliptin effectively improves glycemic control in patients with type 2 diabetes by modulating incretin hormone activity. Januvia has been proven to be an effective and well-tolerated treatment option for managing diabetes.
