Description

L-Tiroxine (Levothyroxine Sodium) Tablets 50 mcg. №50

Ingredients

Active ingredient: Levothyroxine sodium. Inactive ingredients may vary.

Mechanism of Action

Levothyroxine sodium, a synthetic form of the thyroid hormone thyroxine, acts by replacing or supplementing thyroid hormone in cases of inadequate endogenous production.

Pharmacological Properties

Levothyroxine sodium exerts its effects by directly affecting the metabolic processes in the body, regulating energy production and metabolism through interactions with thyroid hormone receptors.

Indications for Use

Indications: L-Tiroxine is prescribed for the management of hypothyroidism, thyroid hormone replacement therapy, and certain types of goiters characterized by thyroid hormone deficiency.

Contraindications

Contraindications: L-Tiroxine should not be administered in cases of untreated thyrotoxicosis, acute myocardial infarction, or uncorrected adrenal insufficiency due to potential adverse effects.

Side Effects

Common side effects of L-Tiroxine may include palpitations, tremors, weight loss, and gastrointestinal disturbances. Adverse reactions are typically dose-dependent and may resolve with dosage adjustments or discontinuation.

Usage Instructions

Dosage: The usual initial dose of L-Tiroxine is 50 mcg taken orally once daily. Dosage adjustments should be made based on individual response and as directed by a healthcare provider.

Administration: Take L-Tiroxine on an empty stomach, at least 30 minutes before consuming food or other medications, to ensure optimal absorption.

Benefits Compared to Analogues

L-Tiroxine, containing levothyroxine sodium as the active ingredient, offers a stable and reliable option for thyroid hormone replacement therapy, providing consistent dosing and efficacy in managing hypothyroidism compared to alternative preparations.

Suitable Patient Groups

L-Tiroxine is suitable for adult patients, including the elderly, and children with hypothyroidism or thyroid hormone deficiencies requiring treatment. Dosage adjustments may be necessary in specific populations based on individual needs and response.

Storage and Shelf Life

• Storage: Keep L-Tiroxine at room temperature, protected from moisture and heat, to maintain its stability and potency.
• Shelf Life: Check the expiration date on the packaging and do not use L-Tiroxine beyond the stated shelf life to ensure efficacy and safety.

Packaging Description

L-Tiroxine is available in blister packs containing 50 tablets of 50 mcg strength each, providing a convenient and accurate dosing regimen for patients requiring thyroid hormone replacement therapy.

Clinical Evidence and Proven Effectiveness

Studies have demonstrated the efficacy of levothyroxine sodium in improving symptoms of hypothyroidism, restoring thyroid hormone levels to normal ranges, and enhancing the quality of life in affected individuals. Proper thyroid hormone replacement therapy with levothyroxine has been shown to reduce complications associated with untreated hypothyroidism, emphasizing its clinical importance and effectiveness.