Description

Lamifen Tablets 250 mg. №28

Ingredients:

Each tablet contains 250 mg of Lamifen (Terbinafine Hydrochloride) as the active ingredient.

Mechanism of Action:

Lamifen (Terbinafine) exerts its antifungal effects by inhibiting squalene epoxidase, an enzyme crucial for fungal ergosterol biosynthesis. This disruption leads to the accumulation of squalene and depletion of ergosterol, resulting in fungal cell membrane damage and growth inhibition.

Pharmacological Properties:

• Antifungal agent
• Works by disrupting fungal cell membrane integrity
• High tissue penetration and bioavailability

Indications for Use:

Lamifen tablets are specifically indicated for the treatment of dermatophytosis, including tinea corporis, tinea cruris, tinea pedis, and onychomycosis caused by susceptible fungal pathogens.

Contraindications:

Avoid the use of Lamifen tablets in individuals with a known hypersensitivity to terbinafine or any other components of the formulation. Prior consultation with a healthcare provider is essential before initiating treatment.

Side Effects:

Common side effects may include gastrointestinal disturbances, rash, taste disturbances, and elevated liver enzymes. Severe adverse reactions such as hepatotoxicity and severe skin reactions are rare but possible.

Usage Instructions:

For adults, the typical dosage regimen involves taking one 250 mg tablet orally once daily. It is advisable to swallow the tablet whole with water, regardless of food intake. Adherence to the prescribed dosage and treatment duration is crucial for optimal therapeutic outcomes.

Benefits Compared to Analogues:

Lamifen tablets offer superior efficacy in the treatment of fungal infections due to their potent antifungal action and favorable pharmacokinetic profile. The high tissue concentrations achieved with Lamifen contribute to enhanced treatment success rates compared to alternative antifungal agents.

Suitable Patient Groups:

Lamifen tablets are generally safe for use in adults, including the elderly population. However, caution is advised in pediatric patients and pregnant or lactating women, and treatment should be initiated under medical supervision in these groups.

Storage Conditions and Shelf Life:

Store Lamifen tablets in a cool, dry place away from direct sunlight to maintain their stability and efficacy. Adhere to the expiration date indicated on the packaging to ensure the product’s potency and safety.

Packaging Description:

Lamifen tablets are supplied in blister packs containing 28 tablets. Each tablet is film-coated for oral administration and is imprinted with the product name and strength for easy identification.

Clinical Evidence and Proven Effectiveness:

Lamifen (Terbinafine) has been extensively studied in clinical trials, demonstrating significant efficacy in the treatment of superficial fungal infections. Research has validated its role in eradicating dermatophytes and improving nail infections, showcasing its clinical utility and therapeutic benefits.