Description
Lorista H Coated Tablets 50 mg/12.5 mg. №60
Ingredients
- Lorista H tablets contain 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide as active ingredients.
- Inactive ingredients include lactose, microcrystalline cellulose, and magnesium stearate.
Dosage
The recommended dosage of Lorista H is one tablet once daily. Follow the instructions provided by your healthcare provider for the correct dosage and duration of treatment.
Indications
Lorista H tablets are indicated for the treatment of hypertension in patients not adequately controlled by losartan or hydrochlorothiazide alone.
Contraindications
- Avoid Lorista H tablets if allergic to any ingredients, pregnant, or have severe renal impairment.
- Consult with your doctor before starting this medication.
Directions
- Take Lorista H tablets orally with or without food as directed by your healthcare provider.
- Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
Scientific Evidence
Studies have shown that the combination of losartan and hydrochlorothiazide in Lorista H tablets effectively lowers blood pressure in hypertensive patients.
Research indicates that the dual therapy provides better blood pressure control compared to monotherapy with losartan or hydrochlorothiazide alone.
Additional Information
- Regularly monitor blood pressure while taking Lorista H tablets.
- Avoid alcohol consumption as it may increase the risk of side effects.
- If severe side effects occur, such as dizziness or difficulty breathing, seek immediate medical attention.
Pharmacological Effects
Losartan blocks the action of angiotensin II, a substance that constricts blood vessels, while hydrochlorothiazide helps the kidneys remove excess salt and water, leading to decreased blood volume and lower blood pressure.
Clinical Trials
Clinical trials have demonstrated the efficacy and safety of Lorista H in managing hypertension.
A study published in the American Journal of Hypertension showed that the combination therapy effectively reduced systolic and diastolic blood pressure levels.
