Description

Metotab (Methotrexate) Tablets 2.5 mg. №100

Ingredients

• Active ingredient: Methotrexate 2.5 mg per tablet.

Dosage

• Dosage: The usual adult dosage of Metotab is 7.5 mg once weekly, taken as a single dose or divided into 2.5 mg every 12 hours for 3 doses. Dosage may vary based on the condition being treated.

Indications

• Indications: Metotab is indicated for the treatment of various conditions including rheumatoid arthritis, psoriasis, leukemia, and lymphoma.

Contraindications

• Contraindications: Do not use Metotab if you are pregnant, breastfeeding, have liver disease, or a history of alcohol abuse.

Directions

• Directions: Take Metotab exactly as prescribed by your healthcare provider. Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet.

Scientific Evidence

• Metotab (Methotrexate): Methotrexate inhibits dihydrofolate reductase, an enzyme involved in DNA, RNA, and protein synthesis, helping to suppress the immune system in conditions like rheumatoid arthritis and psoriasis.
• Research supports methotrexate’s efficacy in reducing disease activity and improving symptoms in rheumatoid arthritis. Clinical trials have shown its ability to induce and maintain remission in certain leukemias and lymphomas.

Additional Information

• Regular monitoring of blood counts and liver function tests is crucial while taking Metotab to prevent potential side effects.
• Common side effects may include nausea, vomiting, and liver toxicity. Contact your healthcare provider if you experience adverse reactions.
• Inform your healthcare provider about all medications you are taking to avoid potential drug interactions.