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Nalbufin (nalbuphine hydrochloride) ampoules 10 mg/ml. 2 ml. №5

$41.00

Purpose: Nalbuphine acts as a mixed opioid agonist-antagonist for pain relief.

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SKU: MED59883 Category:

Description

Nalbufin (nalbuphine hydrochloride) Ampoules 10 mg/ml. 2 ml. №5

Ingredients:

  • Each ampoule contains 10 mg of nalbuphine hydrochloride.

Dosage:

  • The recommended dosage is determined by a healthcare provider based on individual needs.
  • Nalbufin is typically administered via intramuscular or intravenous injection.

Indications:

  • Nalbufin is indicated for the relief of moderate to severe pain.
  • Commonly used in postoperative settings, labor and delivery, and chronic pain management.

Contraindications:

  • Do not use Nalbufin in patients with a known hypersensitivity to nalbuphine hydrochloride or in those with respiratory depression.
  • Caution is advised in patients with a history of substance abuse.

Directions:

  • Administer Nalbufin as directed by a healthcare professional.
  • The injection should be given slowly to minimize the risk of adverse effects.

Scientific Evidence:

Nalbufin, a mixed opioid agonist-antagonist, provides effective pain relief with a lower risk of respiratory depression compared to pure opioid agonists. Studies have shown its efficacy in various pain conditions, making it a valuable option in pain management protocols.

Additional Information:

  • Nalbufin’s unique pharmacological profile allows for effective pain control while reducing the potential for abuse and dependence seen with traditional opioids.
  • Clinical trials have demonstrated its efficacy in providing analgesia comparable to morphine but with a more favorable side effect profile.

Pharmacological Effects: Nalbufin acts as a kappa-opioid receptor agonist and a mu-opioid receptor antagonist, producing analgesia through multiple mechanisms. Its dual action results in a ceiling effect on respiratory depression, making it a safer option in patients at risk for opioid-related complications.

Comparative Effectiveness: In comparative studies, Nalbufin has shown similar analgesic efficacy to morphine in acute pain settings while causing less sedation and respiratory depression. Its unique pharmacodynamic profile makes it a valuable alternative in pain management, especially in patients with respiratory compromise.

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