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Nalbufin (nalbuphine hydrochloride) ampoules 20 mg/1 ml. 1ml. №5

$36.00

Purpose: Nalbuphine inhibits pain signals, used for moderate to severe pain relief.

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SKU: MED59884 Category:

Description

Nalbufin (Nalbuphine Hydrochloride) Ampoules 20 mg/1 ml. 1ml. №5

Ingredients:

  • Each ampoule contains 20 mg of nalbuphine hydrochloride in 1 ml solution.

Dosage:

  • The usual adult dose is 10-20 mg administered intramuscularly every 3-6 hours as needed for pain relief.

Indications:

  • Nalbufin is indicated for the relief of moderate to severe pain. It is commonly used in postoperative settings, labor and delivery, and in chronic pain management.

Contraindications:

  • Do not use Nalbufin in patients with a known hypersensitivity to nalbuphine or other opioid analgesics. It should be used with caution in patients with respiratory depression, head injuries, and acute abdominal conditions.

Directions:

  • Administer Nalbufin by deep intramuscular injection. Avoid intravenous administration. Follow the healthcare provider’s instructions for dosage and frequency.

Scientific Evidence:

  • Nalbufin, a mixed opioid agonist-antagonist, has been shown to provide effective pain relief with a lower risk of respiratory depression compared to pure opioid agonists. Studies have demonstrated its efficacy in various pain conditions, making it a valuable option in pain management protocols.

Additional Information:

  • Nalbufin’s unique pharmacological profile allows for effective pain control while reducing the potential for abuse and dependence seen with traditional opioid medications. Its dual action on opioid receptors provides a balanced analgesic effect, making it a versatile choice for different types of pain.

Pharmacological Effects:

  • Nalbufin acts as a kappa-opioid receptor agonist and a mu-opioid receptor antagonist, producing analgesia without significant respiratory depression. This dual mechanism of action contributes to its safety profile and reduced risk of overdose compared to pure mu-opioid agonists.

Clinical Trials:

  • Clinical trials have shown Nalbufin to be effective in managing acute and chronic pain conditions, including postoperative pain, cancer pain, and labor pain. Its unique pharmacological properties make it a valuable addition to pain management strategies, offering a balance between analgesia and side effect profile.

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