Description
Neotrizol (Ornidazole, Neomycin) Vaginal Tablets №8
Ingredients
- Ornidazole – 500mg
- Neomycin – 100mg
Dosage
The usual dosage is one vaginal tablet inserted into the vagina once daily, preferably at bedtime, for 8 consecutive days.
Indications
Neotrizol vaginal tablets are indicated for the treatment of bacterial vaginosis and trichomoniasis.
Contraindications
Do not use Neotrizol vaginal tablets if you are allergic to any of the ingredients or if you have a history of hypersensitivity to nitroimidazole derivatives.
Directions
Insert one vaginal tablet deep into the vagina using the applicator provided. Wash hands before and after use.
Scientific Evidence
Studies have shown that the combination of ornidazole and neomycin in Neotrizol vaginal tablets is effective in treating bacterial vaginosis and trichomoniasis. Ornidazole exhibits antimicrobial activity against anaerobic bacteria and protozoa, while neomycin helps to control bacterial infections.
Pharmacological Effects
Ornidazole disrupts the DNA structure of microorganisms, leading to their death. Neomycin inhibits bacterial protein synthesis, aiding in the eradication of infections. The combination provides a broad-spectrum antimicrobial effect, targeting the causative agents of vaginal infections.
Clinical Trials
A randomized controlled trial demonstrated the superior efficacy of Neotrizol vaginal tablets in resolving symptoms of bacterial vaginosis compared to standard treatments. The safety profile of the medication was highlighted with minimal reported side effects.