Description
Nistatin (Nistatinum) Coated Tablets 250,000 IU №20
Ingredients:
- Each coated tablet contains 250,000 IU of Nistatin (Nistatinum) as the active ingredient.
- Other ingredients include lactose monohydrate, maize starch, colloidal anhydrous silica, and magnesium stearate.
Dosage:
The usual dose for adults is 1 to 2 tablets four times daily. Dosage may vary based on the severity of the condition and should be determined by a healthcare professional.
Indications:
Nistatin coated tablets are indicated for the treatment of fungal infections caused by Candida species. These infections may affect the skin, mouth, esophagus, or other parts of the body.
Contraindications:
Do not use Nistatin tablets if you are allergic to any of the ingredients. Consult your doctor before use if you are pregnant, breastfeeding, or have any medical conditions.
Directions:
Swallow the tablets whole with a full glass of water. It is important to complete the full course of treatment as prescribed, even if symptoms improve.
Scientific Evidence:
Nistatin is a well-established antifungal medication with a long history of use in treating various fungal infections. Studies have shown its efficacy in combating Candida infections, making it a first-line treatment in many cases. Research published in the Journal of Antimicrobial Chemotherapy has highlighted the effectiveness of Nistatin in treating oral candidiasis, a common fungal infection in the mouth.
Additional Information:
- It is important to store Nistatin tablets in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- If you experience any severe side effects or allergic reactions, discontinue use and seek medical attention immediately.
Pharmacological Effects:
Nistatin works by binding to sterols in the fungal cell membrane, disrupting the membrane integrity and leading to cell death. This mechanism of action makes it highly effective against a wide range of Candida species.
Clinical Trials:
Clinical trials have demonstrated the safety and efficacy of Nistatin in treating fungal infections. A study published in the Journal of Infectious Diseases showed that Nistatin was effective in treating esophageal candidiasis with a high cure rate and minimal side effects.