Description

Pilocarpine (Pilocarpine) Eye Drops 10 mg/ml – 10 ml Vial

Ingredients

Active ingredient: Pilocarpine hydrochloride 10 mg/ml.

Dosage

Dosage: The usual dose is 1 to 2 drops in the affected eye(s) every 4 to 6 hours.

Indications

Indications: Pilocarpine eye drops are used to treat glaucoma and reduce intraocular pressure.

Contraindications

Contraindications: Avoid using pilocarpine eye drops if allergic to pilocarpine or any other ingredients.

Directions

Directions: Tilt your head back, pull down the lower eyelid, and instill the prescribed drops. Close your eyes for 2 minutes without blinking.

Scientific Evidence

Pilocarpine, a parasympathomimetic agent, stimulates muscarinic receptors in the eye, leading to pupil constriction and increased aqueous humor drainage, reducing intraocular pressure. Studies support pilocarpine’s efficacy in managing glaucoma symptoms.

Additional Information

Possible side effects of pilocarpine eye drops include blurred vision, eye irritation, and headache. Inform your healthcare provider about medical conditions or medications before use. Store at room temperature away from moisture and heat.

Pharmacological Effects

Pilocarpine acts as a cholinergic agonist, stimulating muscarinic receptors. By mimicking acetylcholine, it contracts the ciliary muscle and opens the trabecular meshwork, aiding aqueous humor outflow and reducing intraocular pressure.

Clinical Trials and Comparative Effectiveness

Clinical trials demonstrate pilocarpine’s effectiveness in lowering intraocular pressure and improving ocular symptoms in glaucoma patients. Comparative studies show its efficacy compared to other antiglaucoma medications, with a relatively low incidence of systemic side effects.