Description
Protamin Sulfate Solution for Injections 1000 ME/ml – 10 ml Vial
Ingredients:
- Each ml contains Protamin Sulfate 1000 ME (Mega-Units).
Dosage:
- The dosage should be determined based on individual patient needs and is typically administered by injection into a vein or muscle.
Indications:
- Protamin Sulfate is used for treating heparin overdose or reversing the anticoagulant effects of heparin by binding to heparin and neutralizing its activity.
Contraindications:
- Avoid using Protamin Sulfate in case of known hypersensitivity to the drug and use caution in patients with a history of allergies.
Directions:
- Administer as directed by a healthcare provider and monitor for signs of allergic reactions or adverse effects during administration.
Scientific Evidence:
- Studies have shown Protamin Sulfate’s efficacy in rapidly reversing heparin’s anticoagulant effects, making it a vital antidote in clinical practice.
Additional Information:
- Protamin Sulfate forms a stable complex with heparin, preventing further inhibition of clotting factors and allowing rapid restoration of normal coagulation parameters in patients at risk of bleeding due to heparin therapy.
- Clinical trials support the high effectiveness of Protamin Sulfate in managing heparin-related complications with minimal side effects when used appropriately, establishing its importance as a specific antidote for heparin in various medical settings.





