Description
Rezlod (Dorzolamide) Eye Drops Solution 2% 5 ml Bottle Dropper
Ingredients
- Active ingredient: Dorzolamide 2%
- Other ingredients: Benzalkonium chloride, hydroxyethyl cellulose, mannitol, sodium citrate, sodium hydroxide, and water
Dosage
Dosage: Instill 1 drop in the affected eye(s) 3 times a day
Indications
Indicated for: Lowering intraocular pressure in patients with ocular hypertension or open-angle glaucoma
Contraindications
Contraindications: Hypersensitivity to dorzolamide or any component of the formulation
Directions
Directions: Tilt your head back, pull down the lower eyelid, and instill the prescribed number of drops. Close your eye for 2 minutes without blinking
Scientific Evidence
Dorzolamide, the active ingredient in Rezlod, is a carbonic anhydrase inhibitor that reduces intraocular pressure by decreasing aqueous humor production. Studies have shown its efficacy in lowering intraocular pressure and its role as an adjunctive therapy in glaucoma management
Additional Information
Pharmacological Effects: Dorzolamide inhibits carbonic anhydrase in the ciliary processes of the eye, reducing aqueous humor production and lowering intraocular pressure. This mechanism helps in the management of glaucoma and ocular hypertension
Clinical Trials: Clinical trials have demonstrated the efficacy of dorzolamide in reducing intraocular pressure. A study by Realini et al. (2018) showed that dorzolamide, when used as an adjunctive therapy, significantly lowered intraocular pressure in patients with open-angle glaucoma