Description
Sonapax (Thioridazine Hydrochloride) Coated Tablets 25 mg. №60
Ingredients
- Active ingredient: Thioridazine hydrochloride 25 mg.
Dosage
- Dosage: The usual adult dose is 25-50 mg 2-4 times daily, or as directed by a healthcare professional.
Indications
- Indications: Sonapax is indicated for the treatment of schizophrenia and other psychotic disorders.
Contraindications
- Contraindications: Do not use Sonapax in patients with a known hypersensitivity to thioridazine or other phenothiazines.
Directions
- Directions: Swallow the tablets whole with a full glass of water. Do not crush or chew the tablets.
Scientific Evidence
Sonapax (thioridazine hydrochloride) has been extensively studied for its efficacy in managing schizophrenia. Research published in the Journal of Clinical Psychopharmacology demonstrated that thioridazine is effective in reducing positive symptoms of schizophrenia, such as hallucinations and delusions, with a favorable side effect profile compared to other antipsychotic medications.
Additional Information
- It is important to monitor patients regularly for cardiac side effects while on Sonapax therapy, as thioridazine has been associated with QT prolongation and potentially fatal arrhythmias.
- Pharmacological Effects: Thioridazine hydrochloride exerts its antipsychotic effects by blocking dopamine receptors in the brain, particularly the D2 receptors. This action helps to alleviate symptoms of psychosis and schizophrenia.
- Clinical Trials: Clinical trials have shown that Sonapax is effective in managing both positive and negative symptoms of schizophrenia, improving overall quality of life for patients. Comparative studies have indicated that thioridazine may have a lower risk of extrapyramidal side effects compared to other typical antipsychotics.
