Description
Transuloza (lactulose) Paste for Oral Use 150 g Vial
Ingredients
- Active ingredient: Lactulose
- Other ingredients: Purified water, sorbitol, sodium benzoate, and citric acid
Dosage
- Adults: Take 10-20 grams (15-30 mL) daily, divided into 2-3 doses
- Children: Dosage should be adjusted based on age and weight
Indications
Transuloza paste is indicated for the treatment of constipation and hepatic encephalopathy.
Contraindications
Do not use Transuloza paste if you are allergic to any of the ingredients. Consult a healthcare provider before use if pregnant or breastfeeding.
Directions
Mix the prescribed dose with water or juice and drink immediately. Follow with additional water. Adjust dosage based on individual response.
Scientific Evidence
Pharmacological Effects: Lactulose is a synthetic disaccharide that is not absorbed in the small intestine but is fermented by colonic bacteria, leading to an increase in osmotic pressure and acidification of the colonic contents. This results in the retention of water in the colon, softening the stool and promoting bowel movements.
Clinical Trials: Clinical studies have shown that lactulose is effective in the treatment of chronic constipation and hepatic encephalopathy. A study published in the Journal of Gastroenterology and Hepatology demonstrated that lactulose significantly reduced blood ammonia levels in patients with hepatic encephalopathy, leading to improved mental status and quality of life.
Additional Information
Transuloza paste may cause bloating and flatulence initially. These side effects usually subside with continued use. Ensure adequate fluid intake while using this medication.
