Description
Captopril (Captopril) Tablets 25 mg. №40
Ingredients:
Each tablet contains 25 mg of captopril as the active ingredient.
Mechanism of Action:
Captopril, an angiotensin-converting enzyme (ACE) inhibitor, functions by inhibiting the conversion of angiotensin I to angiotensin II. This inhibition results in vasodilation, decreased aldosterone secretion, and reduced sodium retention, leading to a decrease in blood pressure.
Pharmacological Properties:
The pharmacological properties of captopril include its ability to lower blood pressure, improve cardiac function in heart failure, and enhance post-myocardial infarction survival rates.
Indications for Use:
Captopril is indicated for the treatment of hypertension, heart failure, and to enhance survival following a heart attack.
Contraindications:
Avoid taking captopril if you are pregnant, have a history of angioedema associated with previous ACE inhibitor use, or if you are allergic to ACE inhibitors.
Side Effects:
- Dizziness
- Cough
- Hyperkalemia
Contact your healthcare provider if you experience severe dizziness or signs of angioedema while using captopril.
Usage Instructions:
The typical starting dose of captopril is 25 mg taken two or three times daily. Your physician may adjust the dosage according to your specific medical condition.
Benefits Compared to Analogues:
Captopril has demonstrated efficacy in lowering blood pressure and improving outcomes in heart failure patients, as evidenced by clinical trials.
Suitable Patient Groups:
Captopril can be used in various patient populations, including adults, elderly individuals, and pediatric patients under appropriate medical supervision.
Storage and Shelf Life:
Store captopril at room temperature, away from moisture and heat. Ensure it is kept out of the reach of children. Check the expiration date on the packaging and do not use expired medication.
Packaging Description:
Captopril tablets are available in a packaging of 40 tablets, with each tablet containing 25 mg of the active ingredient captopril.
Clinical Evidence and Proven Effectiveness:
Captopril has been extensively studied in clinical trials. For instance, a randomized controlled trial conducted by Yusuf et al. demonstrated that captopril reduces mortality and morbidity in patients post-myocardial infarction. Additionally, captopril has shown consistent efficacy in lowering blood pressure and improving cardiac function in heart failure patients.
