Description
Carbamazepin (Carbamazepine) Tablets 0.2 g. №20
Composition
Each tablet of Carbamazepin contains 0.2 g of carbamazepine as the active ingredient.
Mechanism of Action
Carbamazepine exerts its therapeutic effects by stabilizing the inactivated state of voltage-gated sodium channels, thereby reducing repetitive neuronal firing.
Pharmacological Properties
Carbamazepine is an anticonvulsant drug that also possesses analgesic properties. It acts by modulating sodium channels in neurons, leading to decreased excitability.
Indications for Use
Carbamazepin is indicated for the management of epilepsy, trigeminal neuralgia, and bipolar disorder. It is effective in controlling seizures and neuropathic pain associated with these conditions.
Contraindications
- Patients with a known hypersensitivity to carbamazepine or structurally related compounds should not use Carbamazepin.
- Individuals with a history of bone marrow depression are contraindicated from using this medication.
- Carbamazepin is contraindicated in patients with a history of porphyria due to the potential for exacerbation of symptoms.
Side Effects
Common side effects of Carbamazepin may include dizziness, drowsiness, nausea, and skin rashes. Serious side effects such as agranulocytosis and liver toxicity are rare but possible.
Usage Instructions
For adults, the recommended initial dosage of Carbamazepin is 200 mg taken twice daily. Dosage adjustments should be made based on individual response and tolerability. The tablets should be swallowed whole with water and can be taken with or without food.
Advantages Over Analogues
Carbamazepin offers the advantage of being effective in treating multiple conditions such as epilepsy, trigeminal neuralgia, and bipolar disorder, providing a comprehensive therapeutic option in a single medication.
Suitable Patient Groups
Carbamazepin is suitable for use in both adult and pediatric populations for the approved indications. However, dosage adjustments may be necessary in elderly patients due to potential age-related changes in drug metabolism.
Storage and Shelf Life
Store Carbamazepin tablets in a cool, dry place away from moisture and sunlight. Ensure the packaging is tightly closed. The shelf life of the product is typically stated on the packaging and should be adhered to for optimal efficacy.
Packaging Description
Carbamazepin tablets are typically packaged in blister packs to ensure individual tablet integrity and protection from external factors. The packaging should include essential information such as dosage instructions, expiration date, and batch number for traceability.
