Description
Carboplatin Medak Concentrate for Infusions 10 mg/ml. 45 ml. Vial №1
Composition
The active ingredient in Carboplatin Medak Concentrate is Carboplatin. Each milliliter of the concentrate contains 10 mg of Carboplatin.
Mechanism of Action
Carboplatin exerts its cytotoxic effects by forming intrastrand and interstrand cross-links in DNA, which inhibits DNA replication and transcription, ultimately leading to cell death.
Pharmacological Properties
Carboplatin is a platinum-containing antineoplastic agent that belongs to the alkylating agent class. It is cell-cycle non-specific and works by disrupting DNA synthesis in rapidly dividing cancer cells.
Indications for Use
Carboplatin Medak is indicated for the treatment of advanced ovarian carcinoma of epithelial origin, non-small cell lung cancer, and various other solid tumors.
Contraindications
- Patients with severe bone marrow depression
- Patients with severe kidney impairment
- Patients with a history of severe allergic reactions to cisplatin or other platinum-containing compounds
- Pregnant and breastfeeding women
Side Effects
Common side effects of Carboplatin Medak may include myelosuppression, gastrointestinal disturbances, neurotoxicity, ototoxicity, and allergic reactions. Patients should be monitored closely for adverse effects during treatment.
Usage Instructions
Carboplatin Medak is for intravenous use only. The dosage and administration schedule should be determined by a healthcare professional specializing in oncology based on the patient’s condition and response to treatment.
Benefits Compared to Analogues
Carboplatin Medak offers the advantage of a favorable safety profile compared to other platinum-containing chemotherapeutic agents. It has demonstrated efficacy in various cancer types with manageable side effects.
Suitable Patient Groups
Carboplatin Medak can be used in adult patients, including the elderly, with careful monitoring of renal and hematologic function. It is not recommended for use in pediatric populations due to limited safety data in this age group.
Storage and Shelf Life
Carboplatin Medak Concentrate should be stored at controlled room temperature (20-25°C) and protected from light. The shelf life of the product is as indicated on the packaging.
Packaging Description
Carboplatin Medak Concentrate is supplied in a 45 ml vial for intravenous infusion. Each vial is labeled with the necessary information regarding the product name, concentration, and volume.
