Description

Abixa (memantine) Coated Tablets 10 mg. №28

Ingredients

Active ingredient: Memantine hydrochloride.
Other ingredients: Microcrystalline cellulose, colloidal anhydrous silica, talc, magnesium stearate, hypromellose, macrogol 4000, titanium dioxide (E171).

Dosage

Recommended dosage: The usual starting dose is 5 mg once daily. The dose is then increased by 5 mg at weekly intervals. The maximum recommended dose is 20 mg per day.

Indications

Abixa (memantine) coated tablets are indicated for the treatment of moderate to severe Alzheimer’s disease.

Contraindications

Do not use Abixa (memantine) coated tablets if:

• You are allergic to memantine or any other ingredients in the product.
• You have severe kidney problems.
• You are pregnant or breastfeeding.

Directions

Take Abixa (memantine) coated tablets exactly as prescribed by your healthcare provider. Swallow the tablets whole with water. Do not crush or chew the tablets.

Scientific Evidence

Memantine has shown efficacy in improving cognitive function and reducing the decline in activities of daily living in patients with Alzheimer’s disease. Several clinical trials have demonstrated the benefits of memantine in the treatment of moderate to severe Alzheimer’s disease. For example, a study published in the Journal of Alzheimer’s Disease reported that memantine treatment was associated with significant improvements in cognitive function and global clinical status compared to placebo.

Additional Information

It is important to follow your healthcare provider’s instructions carefully when taking Abixa (memantine) coated tablets. Inform your doctor about any other medications you are taking to avoid potential drug interactions. Regular monitoring of kidney function may be necessary during treatment with memantine.

Memantine works by blocking the activity of glutamate, a neurotransmitter involved in learning and memory. By modulating glutamate levels, memantine helps regulate brain function and improve cognitive symptoms in Alzheimer’s disease.

Compared to other Alzheimer’s medications, memantine has a unique mechanism of action that targets the glutamatergic system. This differentiates it from cholinesterase inhibitors, offering an alternative treatment option for patients who may not respond well to or tolerate cholinesterase inhibitors.