Description
Accupro (Quinapril) Coated Tablets 20 mg. №30
Composition
Active ingredient: Quinapril 20 mg.
Other ingredients: lactose monohydrate, microcrystalline cellulose, crospovidone, magnesium stearate, hypromellose, polyethylene glycol, titanium dioxide, and more.
Mechanism of Action
Pharmacological Properties: Quinapril is an ACE inhibitor that blocks the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting this process, quinapril promotes vasodilation, reduces blood pressure, and enhances cardiac output.
Indications for Use
Accupro (Quinapril) coated tablets are indicated for the management of hypertension and congestive heart failure.
Contraindications
Do not use Accupro (Quinapril) coated tablets if:
- You are allergic to quinapril or any other ACE inhibitor.
- You have a history of angioedema.
- You are pregnant.
Side Effects
Common side effects may include dizziness, cough, hypotension, and hyperkalemia. Contact your healthcare provider if you experience any adverse reactions.
Usage Instructions
Dosage: The recommended dose is 20 mg once daily. Dosage adjustments may be made based on individual response.
Administration: Take Accupro (Quinapril) coated tablets orally with or without food. Swallow the tablet whole with a full glass of water.
Benefits Compared to Analogues
Accupro has demonstrated efficacy in lowering blood pressure and improving cardiac function, distinguishing it from other ACE inhibitors.
Suitable Patient Groups
Accupro can be used in adult patients for the treatment of hypertension and heart failure. Dosage adjustments may be necessary for elderly individuals.
Storage and Shelf Life
Store Accupro (Quinapril) tablets in a cool, dry place away from moisture and sunlight. Check the expiration date on the packaging and do not use the product beyond that date.
Packaging Description
Accupro (Quinapril) tablets are available in blister packs of 30 coated tablets each.
Clinical Evidence and Proven Effectiveness
Scientific Evidence: Studies have confirmed the efficacy of quinapril in reducing blood pressure and enhancing cardiac function in patients with hypertension and heart failure.
Clinical Trials: Clinical trials have shown that quinapril reduces cardiovascular events and mortality rates in patients with heart failure and hypertension. For example, a study published in the New England Journal of Medicine reported a significant decrease in heart failure-related hospitalizations with quinapril treatment compared to a placebo.