Accupro (quinapril) coated tablets 10 mg. №30

$32.00

Manufacturer: Germany

Out of stock

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Description

Composition

active ingredient: quinapril;

1 tablet contains quinapril hydrochloride in amounts equivalent to 5 mg or 10 mg or 20 mg quinapril;

Excipients: magnesium carbonate; gelatin; lactose monohydrate, crospovidone; magnesium stearate candelilla wax; Opadry white OY-S-7331 (hypromellose, titanium dioxide (E 171), hydroxypropyl methylcellulose, polyethylene glycol 400).

Indications.

Essential hypertension.

Heart failure – as an auxiliary drug in combination with diuretics, especially in severe heart failure – in combination with digitalis preparations.

Contraindications.

– Hypersensitivity to the components of the drug.

– a history of angioedema or other angioedema (for example, as a result of previous treatment with ACE inhibitors).

– Combination with sacubitril / valsartan, due to an increased risk of angioedema.

– Bilateral stenosis of the renal arteries or stenosis of the artery of a single kidney.

– after kidney transplantation.

– Hemodynamically significant aortic or mitral valve stenosis or hypertrophic cardiomyopathy.

– primary hyperaldosteronism.

– Pregnancy (see Section “Use during pregnancy or lactation”).

– Breast-feeding (see Section “Use during pregnancy or lactation”).

Do not use drugs containing aliskiren together with quinapril in patients with diabetes mellitus or renal insufficiency (glomerular filtration rate GFR <60 ml / min / 1.73 m2) (see Sections “Interaction with other medicinal products and other types of interactions” and “Pharmacological “).

During therapy with Accupro, dialysis or hemofiltration using field (acrylonitrile, sodium-2-methylallylsulfonate) -high-flow membranes (for example “AN69”) is contraindicated, since there is a risk of developing hypersensitivity reactions (anaphylactic reactions), including life-threatening shock, during dialysis or hemofiltration.

If emergency dialysis or hemofiltration is necessary, the drug should first be replaced with another drug that is not an ACE inhibitor, or alternative dialysis membranes should be used (see section “Peculiarities of use”).

Life-threatening hypersensitivity reactions have been observed during low-density lipoprotein apheresis (for severe hypercholesterolemia) with dextran sulfate and concomitant use of an ACE inhibitor.

Sometimes life-threatening hypersensitivity reactions (eg, low blood pressure, shortness of breath, vomiting, allergic skin reactions) may occur during treatment to reduce or eliminate the tendency to develop allergic reactions (desensitizing therapy) to insect toxins (such as bee or wasp stings) , and concomitant use of an ACE inhibitor.

If low-density lipoprotein (LDL) apheresis or desensitizing therapy for insect toxins is necessary, the drug should be temporarily replaced with other drugs intended for the treatment of arterial hypertension or heart failure.

Method of application and dose.

Accupro can be taken with or without food; the daily dose can be used at a time or divided into 2 doses. The duration of use is determined by the doctor.