Adaptol (mebikar) capsules 300 mg. №20

Description

Composition

active substance: mebicar;

1 capsule contains mebicar 300 mg;

excipients: methylcellulose, calcium stearate, titanium dioxide (E 171), gelatin. 

Pharmacological group

Anxiolytics. ATX code N05B X.

Pharmacodynamics.

The active substance of the drug Adaptol® – mebicar – is close in chemical structure to the natural metabolites of the body: its molecule consists of two methylated urea fragments that are part of the bicyclic structure. Adaptol® has a moderate tranquilizing (anxiolytic) activity, relieves or weakens feelings of anxiety, anxiety, fear, internal emotional stress and irritation. The calming effect of the drug is not accompanied by muscle relaxation and impaired coordination of movements. The drug reduces mental and motor activity, so Adaptol® can be used during the working day or during training. The drug does not create an elevated mood, a feeling of euphoria. On this basis, Adaptol® is classified as a daytime tranquilizer. It does not have a hypnotic effect, but enhances the effect of hypnotics and improves sleep when it is disturbed. In addition to calming, Adaptol® has a nootropic effect. The drug improves cognitive functions, increases attention and mental performance, without stimulating the symptoms of productive psychopathological disorders – delirium, pathological emotional activity. Adaptol® has antioxidant activity, therefore it acts as a membrane stabilizer, adaptogens and cerebroprotectors in oxidative stress of various origins.

Adaptol® acts on the activity of structures included in the limbic-reticular complex, in particular on the emotiogenic zones of the hypothalamus, and also affects all 4 major neurotransmitter systems – GABAergic, cholinergic, serotonergic and adrenergic – does not contribute to their balance of peripheral adrenergic action. The neurotransmitter action profiles of ADAPTOL ® contain a dopamine-positive component. The drug exhibits antagonistic activity in excitation of the adrenergic and glutamatergic systems and enhances the functioning of inhibitory serotonin and GABAergic brain mechanisms. The drug has normasthenic properties. Adaptol® facilitates nicotine withdrawal.  

Indications

• Neuroses and neurosis-like states, accompanied by irritation, emotional lability, feelings of anxiety and fear.
• To improve the tolerance of antipsychotics or tranquilizers in order to eliminate the somatovegetative and neurological side effects caused by them.
• Cardialgia of various origins (not associated with coronary heart disease).
• As part of the complex therapy of nicotine addiction as a means of reducing the craving for smoking.

Contraindications

Hypersensitivity to mebicar or any of the excipients of Mebicar capsules.

Interaction with other medicinal products

Adaptol® can be combined with antipsychotics, tranquilizers (benzodiazepines), sleeping pills, antidepressants and psychostimulants.

Care should be taken when driving vehicles, since the use of the drug can cause a decrease in blood pressure and weakness.

Dosage and administration

Mebicar capsules should be taken orally regardless of food intake. Adults: 300-600 mg 2-3 times a day. If necessary, the dose can be increased. Maximum single dose – 3