Description
Adenuric (Febuxostat) Coated Tablets 80 mg. №28
Ingredients
Active ingredient: Febuxostat 80 mg.
Inactive ingredients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, triacetin.
Mechanism of Action
Febuxostat is a xanthine oxidase inhibitor that decreases the production of uric acid in the body, thereby preventing gout attacks and complications associated with hyperuricemia.
Pharmacological Properties
By lowering uric acid levels, febuxostat effectively manages hyperuricemia in patients with gout, reducing the risk of associated complications.
Indications for Use
Adenuric (febuxostat) tablets are indicated for the management of hyperuricemia in patients with gout, helping to control uric acid levels and prevent gout attacks.
Contraindications
Do not use Adenuric tablets in patients with severe liver disease or a history of severe hypersensitivity reactions to febuxostat to avoid potential adverse reactions.
Side Effects
Adverse reactions may include nausea, rash, and elevated liver enzymes. Monitoring liver function tests is crucial during treatment, especially in patients with pre-existing liver conditions.
Usage Instructions
The recommended dosage of Adenuric tablets is 80 mg once daily. Dosage adjustments may be necessary based on individual response. The tablets should be taken orally with or without food, swallowed whole with water, and not crushed or chewed.
Benefits Compared to Analogues
Clinical studies have shown that febuxostat is superior to allopurinol in achieving target uric acid levels and reducing the rate of gout flares, making it a beneficial option for managing hyperuricemia in patients with gout.
Suitable Patient Groups
Adenuric tablets are suitable for adult patients with gout who require management of hyperuricemia. Dosage adjustments may be necessary for elderly patients or those with specific health conditions; consult a healthcare provider for personalized recommendations.
Storage Conditions and Shelf Life
Store Adenuric tablets in a cool, dry place away from direct sunlight. Check the packaging for the expiration date and do not use the tablets beyond this date.
Packaging Description
Adenuric tablets are coated tablets containing 80 mg of febuxostat. Each package contains 28 tablets for a full treatment course.
Clinical Evidence and Proven Effectiveness
Studies have demonstrated the efficacy of febuxostat in lowering serum uric acid levels in patients with hyperuricemia. In a randomized controlled trial, febuxostat showed superior efficacy compared to allopurinol in achieving target uric acid levels, indicating its effectiveness in managing hyperuricemia in patients with gout.
