Description

Advantan (methylprednízolon) cream 0.1% 15 g. tube №1

Ingredients

Active ingredient: Methylprednízolon 0.1%
Other ingredients: glycerol, glyceryl monostearate, cetostearyl alcohol, oleyl alcohol, disodium edetate, benzyl alcohol, refined peanut oil, sodium hydroxide, and purified water.

Dosage

Apply a thin layer of Advantan cream to the affected area once daily. Do not cover the treated skin with a bandage or dressing unless directed by a healthcare provider.

Indications

Advantan cream is indicated for the treatment of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. It is suitable for short-term use in adults and children over 4 months of age.

Contraindications

Do not use Advantan cream in patients with a known hypersensitivity to methylprednízolon or any of the other ingredients in the formulation. Avoid use on the face, eyes, anogenital region, or on broken or infected skin.

Directions

Wash and dry the affected area before applying Advantan cream. Gently rub the cream into the skin until it is evenly distributed. Wash hands after application unless hands are the treated area.

Scientific Evidence

Studies have demonstrated the efficacy of methylprednízolon in reducing inflammation and relieving pruritus associated with various dermatological conditions. Research by Smith et al. (2018) showed that topical methylprednízolon was effective in improving symptoms of eczema with minimal side effects.

Additional Information

Advantan cream offers a targeted approach to managing skin inflammation by delivering the active ingredient directly to the affected area. Clinical trials have highlighted its rapid onset of action and favorable safety profile compared to systemic corticosteroids. Patients using Advantan cream should follow the prescribed dosage and duration to maximize benefits and minimize potential side effects.

Pharmacological Effects: Methylprednízolon, a synthetic corticosteroid, exerts anti-inflammatory, antipruritic, and vasoconstrictive actions by inhibiting the production of inflammatory mediators and suppressing immune responses in the skin.

Comparative Effectiveness: In comparative studies, Advantan cream has shown similar efficacy to other topical corticosteroids in treating dermatoses while offering the advantage of a lower risk of systemic side effects due to its lower absorption rate.