Description

Aflubin Penciclovir (Penciclovir) Cream 1% 2g

Ingredients

Active ingredient: Penciclovir 1%

Dosage

Dosage: Apply a small amount of cream to the affected area 5 times a day for 4 days.

Indications

Indicated for: Treatment of recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents.

Contraindications

Do not use if: Allergic to penciclovir or any other ingredients in the cream.

Directions

– Wash hands before and after applying the cream.
– Apply enough to cover the affected area.
– Avoid contact with eyes and mucous membranes.

Scientific Evidence

Pharmacological Effects: Penciclovir works by inhibiting viral DNA replication, thus reducing the duration and severity of cold sore outbreaks. It penetrates infected cells and blocks the replication of the herpes simplex virus.

Clinical Trials: Clinical studies have shown that penciclovir cream is effective in reducing the healing time of cold sores compared to placebo. In a double-blind, placebo-controlled trial, patients treated with penciclovir experienced faster lesion healing and symptom resolution.

Comparative Effectiveness: Compared to acyclovir, another antiviral medication used for cold sores, penciclovir has been reported to have a longer intracellular half-life, potentially leading to better efficacy with less frequent dosing.

Overall, Aflubin Penciclovir (Penciclovir) cream 1% 2g is a well-tolerated and effective treatment for cold sores, backed by scientific evidence and clinical trials.