Description
Aflubin Penciclovir (Penciclovir) Cream 1% 2g
Ingredients
Active ingredient: Penciclovir 1%
Mechanism of Action
Penciclovir works by inhibiting viral DNA replication, thus reducing the duration and severity of cold sore outbreaks. It penetrates infected cells and blocks the replication of the herpes simplex virus.
Pharmacological Properties
The pharmacological properties of Penciclovir involve its antiviral action against herpes simplex virus, specifically in reducing viral replication and promoting lesion healing.
Indications for Use
Indicated for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents.
Contraindications
Do not use if allergic to penciclovir or any other ingredients in the cream.
Side Effects
Common side effects may include local skin reactions such as burning or stinging at the application site. In rare cases, allergic reactions may occur. Consult a healthcare provider if any adverse effects are experienced.
Usage Instructions
- Wash hands before and after applying the cream.
- Apply enough to cover the affected area.
- Avoid contact with eyes and mucous membranes.
- Apply a small amount of cream to the affected area 5 times a day for 4 days.
Benefits Compared to Analogues
Compared to acyclovir, penciclovir has a longer intracellular half-life, potentially leading to better efficacy with less frequent dosing. Clinical studies have shown that penciclovir cream is effective in reducing the healing time of cold sores compared to placebo.
Suitable Patient Groups
This cream is suitable for use by immunocompetent adults and adolescents for the treatment of recurrent herpes labialis.
Storage and Shelf Life
Store the cream at room temperature away from moisture and heat. Check the expiration date on the packaging and do not use if expired.
Packaging Description
The cream is packaged in a tube containing 2g of 1% penciclovir formulation.
