Alergocort (triamcinolon) ointment 1 mg/g. 15 g. tube №1

active ingredient : triamcinolone;

1 g of the drug contains triamcinolone acetonide 1 mg;

excipients : methyl paraben (E 218), stearic acid, polysorbate 60, cetostearyl alcohol, mineral oil, glycerin, purified water.

Corticosteroids for use in dermatology.

ATX code D07A B09.

The active substance of the ointment is triamcinolone acetonide-GCS, contains fluorine and, when applied topically, exhibits anti-inflammatory, anti-allergic and antipruritic effects.

The pharmacological action of glucocorticosteroids is based on the regulation of the synthesis of specific body proteins and ensuring the body’s adaptability to stressful situations by reducing glucose utilization and increasing gluconeogenesis (hyperglycemia). They contribute to the deposition of glycogen, primarily in the liver, by increasing the secretion of insulin in conditions of hyperglycemia. GCS reduce the synthesis and increase the catabolism of proteins in muscle, skin and bone tissues and contribute to lipolysis. They constrict blood vessels, reduce their permeability and tissue swelling.

Numerous GCS receptors are also found in the tissues of the brain and heart. GCS enhance β-adrenergic reactions in the lungs, dilate the bronchi and reduce vascular resistance in the lungs.

In high doses, corticosteroids inhibit the secretion of corticotropin, with adrenocorticosteroid insufficiency, they increase glomerular filtration and diuresis; cause ulcerative lesions of the mucous membranes. In large doses, they exhibit anti-allergic and anti-inflammatory properties.

The esterification of the GCS molecule with fatty acids in the 17th and 21st positions significantly enhances its effect on the skin. The location of the cyclic acetonide in the 16th and 17th positions enhances the local anti-inflammatory effect without affecting the systemic effect of GCS. Fluorine contributes to a further increase in the local activity of the drug.

Triamcinolone penetrates well into the deep layers of the skin, partially enters the bloodstream. When applying an occlusive dressing to the affected skin areas, it is absorbed in an amount sufficient for a systemic effect. GCS are rapidly distributed in body tissues. The main metabolite of triamcinolone-6-β-hydroxytriamcinolone is excreted by the liver, kidneys, feces and urine in equal proportions. The half-life is about 5 hours, the half-life is 18-36 hours.

Skin diseases sensitive to corticosteroids (eczema, psoriasis vulgaris, allergic dermatitis).

Hypersensitivity to triamcinolone acetonide or to an excipient of the drug.

The drug should not be used in the eyes or on the skin around the eyes.

Do not use as monotherapy without specific treatment for fungal and bacterial skin infections.

Tuberculosis; viral skin lesions, especially with herpes simplex and chicken pox; parasitic infections (scabies); skin manifestations of syphilis; skin reactions after vaccination; perianal and genital itching leg ulcer varicose veins common plaque psoriasis; facial skin lesions (rosacea, acne vulgaris, perioral dermatitis); diaper rash caused by wet diapers; dry peeling of the skin. Do not apply ointment to the breast just before breastfeeding.

Do not use in children under 1 year old.

For external use.

For adults, apply a thin layer of ointment 2-3 times a day to the affected skin area (maximum dose – no more than 15 g of ointment per day) or apply the drug under an occlusive dressing (maximum dose – no more than 10 g of ointment per day).

For children over the age of 1 year, apply a thin layer of ointment a maximum of 2 times a day to the affected area of ​​the skin. The duration of the drug in children should not exceed 5 days. The use of an occlusive dressing is contraindicated in children.

Elderly people should use the drug carefully and for a short time, because in this category of patients the skin is thinner.