AlergoMax (dimethynden maleat) nasal spray 15 ml.

active ingredients: dimethindene maleate, phenylephrine;

1 ml of the drug contains dimethindene maleate 0.25 mg, phenylephrine 2.5 mg;

excipients: citric acid monohydrate, sodium phosphate, anhydrous sorbitol (E 420), benzalkonium chloride, peppermint oil; purified water.

Decongestants and other rhinological preparations for topical use. Sympathomimetics, combinations, with the exception of corticosteroids. ATX code R01A B.

Combined preparation containing phenylephrine and dimethindene.

The drug reduces nasal discharge and helps to cleanse the nasal passages without disturbing the physiological functions of the ciliated epithelium and nasal mucosa.

Phenylephrine is an amine sympathomimetic. It is used as a nasal decongestant with a moderate vasoconstrictive effect, selectively stimulates α1-adrenergic receptors of the cavernous venous tissue of the nasal mucosa. Thus, it quickly and permanently eliminates swelling of the nasal mucosa and paranasal sinuses.

Dimetindene – an H1 receptor antagonist – exhibits an antiallergic effect. Effective at low doses, well tolerated.

The drug is intended for topical use, so its activity does not correlate with the concentration of active substances in the blood plasma.

With accidental oral ingestion, the bioavailability of phenylephrine decreased and accounted for approximately 38% of first-pass metabolism in the intestine and liver, with a half-life of about 2.5 hours.

The systemic bioavailability of dimethindene after oral administration in solution is approximately 70%, the half-life is about 6 hours.

In adults and children over 6 years of age: symptomatic treatment of colds, nasal congestion, acute and chronic rhinitis, seasonal (hay fever) and non-seasonal allergic rhinitis, acute and chronic sinusitis, vasomotor rhinitis. Auxiliary therapy for acute otitis media.

Preparation for surgery in the nasal area, and elimination of swelling of the nasal mucosa and paranasal sinuses after surgery.

Hypersensitivity to phenylephrine, dimethindene maleate or any of the excipients.

Due to the content of phenylephrine, the drug, like other vasoconstrictors, is contraindicated in atrophic rhinitis, angle-closure glaucoma, as well as in patients taking MAO inhibitors (MAO) or who have taken them for the previous 14 days.

The drug, like other sympathomimetics, should be used with caution in patients with a severe reaction to adrenergic substances, manifested by such signs as insomnia, dizziness, tremor, cardiac arrhythmias or increased blood pressure.

The drug should not be used continuously for more than 3 days. If symptoms do not disappear for more than 3 days or worsen, you should consult a doctor. Prolonged or excessive use of the drug can cause tachyphylaxis and a rebound effect (drug rhinitis).

As with other vasoconstrictors, the recommended dose should not be exceeded. Excessive use of the drug, especially in children and elderly patients, can cause manifestations of the systemic effect of the drug.

It should be used with caution in patients with cardiovascular diseases, patients with arterial hypertension, hyperthyroidism, diabetes mellitus and patients with obstruction of the bladder neck (for example, prostatic hypertrophy).

Due to the content of H1-antihistamines dimethindene maleate, the drug should be used with caution in patients with epilepsy.

Before administering the drug, you should thoroughly clean your nose.

Children aged 6 years and older and adults

1-2 injections in each nasal passage 3-4 times a day.

The vial/balloon should be held vertically, spray up. Keeping your head straight, insert the tip into the nasal passage, press the sprayer with a short sharp movement 1 time and, pulling the tip out of the nose, release. During injection, it is recommended to inhale slightly through the nose to evenly distribute the drug. The duration of continuous treatment should not exceed 3 days and depends on the course of the disease.

The use of the drug in children aged 6 to 12 years should be carried out under the supervision of adults.