$12.00
Manufacturer: Hungary
Alerzin is prescribed to eliminate symptoms such as:
- year-round allergic rhinitis, which is accompanied by nasal congestion, sneezing, watery discharge, lacrimation, redness of the eyes;
- seasonal allergic rhinitis;
- chronic idiopathic urticaria;
- allergic dermatosis, which is followed by hives, itching and rashes.
Description
Alerzin (levocetirizine) Composition
active substance: levocetirizine dihydrochloride;
1 tablet contains:
- 5 mg of levocetirizine dihydrochloride (corresponding to 4.21 mg of levocetirizine);
excipients: silicon microcrystalline cellulose, low-substituted hydroxypropyl cellulose, lactose monohydrate, magnesium stearate;
shell composition: Opadry II 33G28523 white (hypromellose, titanium dioxide (E 171), macrogol 3350, triacetylglycerin, lactose monohydrate).
Pharmacotherapeutic group
Antihistamines for systemic use. Piperazine derivatives. ATX code R06A E09.
Pharmacodynamics
Levocetirizine is an active, stable R-enantiomer of cetirizine, which belongs to the group of competitive histamine antagonists. Pharmacological action is due to blocking
H1-histamine receptors. Levocetirizine’s affinity for H1-histamine receptors is 2 times higher than that of cetirizine. It affects the histamine-dependent stage of the development of an allergic reaction, reduces the migration of eosinophils, vascular permeability, and limits the release of inflammatory mediators. Prevents the development and eases the course of allergic reactions, has an anti-exudative, anti-pruritic, anti-inflammatory effect, almost no anti-cholinergic and anti-serotonin effects.
Indication
- Symptomatic treatment of allergic rhinitis (including year-round allergic rhinitis) and urticaria.
Contraindications of Alerzin (levocetirizine)
- Hypersensitivity to levocetirizine, cetirizine, hydroxyzine, to any other piperazine derivatives or to any other excipient of the drug.
- A severe form of chronic renal failure (creatinine clearance <10 ml/min).
- Rare hereditary diseases of galactose intolerance, lactase deficiency or impaired absorption of glucose and galactose.
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