Alfa D3-TEVA (alfacalcidol) capsules 0.5 mcg. №30

Description

Composition

• active ingredient: alfacalcidol;
• 1 capsule contains alfacalcidol 0.25 mcg or 0.5 mcg, or 1 mcg;
• excipients citric acid, propyl gallate, vitamin E (DL-alpha-tocopherol), ethanol, peanut oil, gelatin, glycerin 85%, sorbitol (E 420), sorbitan anhydrides, mannitol (E 421), higher polyols, purified water;
• iron oxide red (E172) for a dose of 0.25 mcg;
• titanium dioxide (E 171), iron oxide red (E172) for a dose of 0.5 mcg;
• titanium dioxide (E 171), iron oxide yellow (E172) for a dose of 1 mcg.

Indications

• Postmenopausal osteoporosis.
• osteoporosis associated with glucocorticoid treatment.
• softening of the bones in old age (osteomalacia) as a result of insufficient absorption, for example, in the case of malabsorption and post-gastroectomy syndrome.
• to significantly reduce the frequency of falls among the elderly.
• with hypoparathyroidism or hypophosphatemic (vitamin d-resistant) rickets/osteomalacia, additional therapy with alpha d3-teva may be indicated if the level of calcium in the blood plasma is 2.2 mmol / l.
• diseases accompanied by a violation of 1-alpha-hydroxylation in the kidneys, which, in turn, cause disturbances in the metabolism of vitamin D (for example, renal osteodystrophy with a decrease in calcium absorption and a calcium level in the blood plasma of 2.2 mmol / l (8.8 mg / 100 ml).

Dosage and Administration

inside. The capsule should be swallowed whole with plenty of water. the dose and duration of therapy are determined by the doctor individually and depend on the nature of the disease and the effectiveness of therapy. in some cases, the drug is used throughout life.

Unless otherwise prescribed by a doctor, the initial dose for adults is 1 mcg of alfacalcidol (4 capsules of 0.25 mcg, or 2 capsules of 0.5 mcg, or 1 capsule of 1 mcg) daily. For patients with more severe bone disease, higher doses of alfacalcidol 1–3 μg (4–12 0.25 μg capsules or 2–6 0.5 μg capsules or 1–3 1 μg capsules) daily are given.

Children over 6 years of age weighing ≥20 kg who can swallow the capsule – 1 mcg / day (except in cases of renal osteodystrophy).

For patients with hypoparathyroidism, the dose should be reduced after a normal blood calcium level (2.2–2.6 mmol/L; 8.8–10.4 mg/100 mL) has been reached, or when the product of plasma calcium • phosphate concentrations is 3.5–3.7 (mmol/l).

Capsules Alpha D ₃ -Teva 0.25 mcg. If the daily dose is 0.5 micrograms of alfacalcidol, take 1 capsule in the morning and evening daily. If the daily dose is 1 mcg of alfacalcidol, take 2 capsules in the morning and evening daily.

Capsules Alpha D ₃ -Teva 0.5 mcg. If the daily dose is 0.5 mcg, take 1 capsule daily in the evening. If the daily dose is 1-3 micrograms of alfacalcidol (2-6 capsules of 0.5 micrograms), it should be divided in half and taken one half in the morning and the other in the evening.

Capsules Alpha D ₃ -Teva 1 mcg. If the daily dose is 1 mcg of alfacalcidol, take 1 capsule daily in the evening. If the daily dose is 3 mcg of alfacalcidol, take 1 capsule in the morning and 2 capsules of Alpha D ₃ -Teva in the evening.

Contraindications

Hypersensitivity to alfacalcidol, peanuts, soy or any other components of the drug; hypersensitivity to vitamin d and manifestations of vitamin d intoxication; plasma calcium level 2.6 mmol/l; product of calcium • phosphate concentrations in blood plasma 3.7 (mmol/l); alkalosis with a ph level of venous blood of 7.44 (lactatalkalosis syndrome, Burnett’s syndrome); metastatic calcification; hypersensitivity to vitamin D analogues.