Description

Allesta (simvastatin) tablets 20 mg. №30

Ingredients

Active ingredient: Simvastatin 20 mg.
Other ingredients: lactose monohydrate, microcrystalline cellulose, pregelatinized starch, and more.

Dosage

Recommended dosage: The usual dose is 20-40 mg once daily in the evening. Dosage adjustments should be made at intervals of 4 weeks or more.

Indications

Indicated for: Lowering high cholesterol and triglycerides levels in the blood. It is also used to reduce the risk of heart attack, stroke, and other heart complications in patients with diabetes or other risk factors.

Contraindications

Do not use if: You are pregnant or breastfeeding, have active liver disease, or are allergic to simvastatin or any other components of the product.

Directions

How to use: Swallow the tablet whole with a full glass of water. It is usually taken in the evening with or without food. Follow the instructions of your healthcare provider.

Scientific Evidence

Pharmacological effects: Simvastatin works by inhibiting HMG-CoA reductase, an enzyme involved in cholesterol synthesis. By lowering cholesterol levels, it reduces the risk of cardiovascular events.

Clinical trials: Several studies have demonstrated the efficacy of simvastatin in reducing LDL cholesterol and the incidence of cardiovascular events. For example, the Scandinavian Simvastatin Survival Study showed a significant reduction in mortality and morbidity in patients treated with simvastatin.

Additional Information

Warnings: Before using Allesta, inform your doctor about any medical conditions or medications you are taking. Regular monitoring of liver function tests is recommended during treatment.

Storage: Store at room temperature away from moisture and heat. Keep out of reach of children.