Almagel A (aluminum hydroxide) suspension 10 ml. №20

active ingredients : aluminum hydroxide, magnesium hydroxide;

10 ml (1 sachet) suspension contains:

• aluminum hydroxide gel 4.36 g in terms of aluminum oxide 436 mg;
• magnesium hydroxide paste 700 mg in terms of magnesium oxide 150 mg;
• benzocaine 218 mg;

excipients: sorbitol (E 420), hydroxyethylcellulose, methyl parahydroxybenzoate (E 218), propyl parahydroxybenzoate (E 216), butyl parahydroxybenzoate, sodium saccharin, lemon oil, ethanol 96%, purified water, hydrogen peroxide solution (30%), propylene glycol, macrogol 4000 .

Preparations for the treatment of acid-dependent diseases. Antacids. aluminum compounds. Combinations. ATX code A02A B10.

Almagel A is a balanced combination of aluminum hydroxide and magnesium hydroxide in combination with sorbitol. The drug has a moderate antacid effect when the recommended single and daily dose is applied within 40-60 minutes after a meal.

Aluminum hydroxide neutralizes the increased secretion of hydrochloric acid and reduces the activity of pepsin in the stomach, forming aluminum chloride. Under the influence of the alkaline environment of the intestine, the latter turns into alkaline aluminum salts, which are almost not absorbed and slightly change the concentration of aluminum salts in the blood with prolonged use of Almagel A. On the other hand, aluminum hydroxide tends to change the concentration of phosphates, binding phosphate ions in the intestine and thus limiting their absorption.

Antacids containing aluminum, including Almagel A, also have a cytoprotective effect on the gastric mucosa, associated with the activation of prostaglandin synthesis. Thus, the resistance of the mucous membrane increases, protecting it from inflammatory-necrotic and erosive-hemorrhagic changes caused by irritating and ulcerogenic agents, such as acetylsalicylic acid, non-steroidal anti-inflammatory drugs, ethanol.

Magnesium hydroxide also neutralizes hydrochloric acid in the stomach, turning into magnesium chloride, which has a slight laxative effect.

Benzocaine has a local anesthetic effect in the presence of severe pain.

Sorbitol has a weak carminative and moderate choleretic and laxative effect. Such effects compensate in most patients for the tendency to constipation under the influence of aluminum hydroxide.

The drug does not lead to the development of alkalosis and the formation of carbon dioxide (CO2) in the stomach.

Short symptomatic treatment of inflammatory and erosive lesions, accompanied by heartburn, discomfort, pain, nausea, vomiting; in acute or chronic inflammatory processes or other disorders of the mucous membranes of the esophagus, stomach or duodenum.

The drug should not be prescribed to children (due to the risk of developing methemoglobinemia), as well as to pregnant and lactating women, given the content of benzocaine.

Almagel A is contraindicated for:

• hypersensitivity to any active and / or excipients that make up the medicinal product;
• hypersensitivity to anesthetics;
• chronic constipation;
• chronic diarrhea;
• severe abdominal pain of unspecified origin, suspected acute appendicitis;
• Alzheimer’s disease;
• severe forms of renal failure (due to the risk of hypermagnesemia and aluminum intoxication);
• hypophosphatemia;
• marked exhaustion of the patient.

Almagel A should be used for the treatment of adults.

Before use, the suspension must be made homogeneous by carefully shaking the vial or gently kneading the sachet. The drug does not need to be diluted or washed down. Measuring the required amount of the drug from the vial occurs by using the dosing spoon, which is contained in the kit. When using the drug in sachets, holding the sachet vertically, cut off or tear off one of the corners in the designated place, pour the contents of the sachet through the hole into a spoon or directly into the oral cavity.

Doses

Apply 1 sachet 3-4 times a day 10-15 minutes before meals.

In the case of prescribing the drug in a single dose of 5 ml, it is recommended to use Almagel A in vials, since this type of package contains a dosing spoon, which makes it possible to accurately measure the required volume of the drug.

The duration of treatment with Almagel A should not exceed 7 days, then, as prescribed by the doctor, you can continue treatment with Almagel.

Kidney failure . In the event of a decrease in renal function, the daily dose should be reduced or the intervals between doses should be lengthened in accordance with the severity of the dysfunction.