Almagel NEO suspension 170 ml.

active substances:

5 ml (1 scoop) suspension contains:

• aluminum hydroxide gel in terms of aluminum hydroxide 340 mg;
• magnesium hydroxide paste in terms of magnesium hydroxide 395 mg;
• emulsions of simethicone 30% in terms of polydimethylsiloxane 36 mg;

excipients: hydrogen peroxide solution (30%), sorbitol (E 420), sodium saccharin, hydroxyethyl cellulose, citric acid, ethyl parahydroxybenzoate (E 214), propyl parahydroxybenzoate (E 216), propylene glycol, macrogol 4000, orange flavor, ethanol 96%, water purified.

Antacids. Combinations of simple salts and carminative (antiflatulents). ATX code A02A F02.

Almagel NEO suspension is a balanced combination of aluminum hydroxide and magnesium hydroxide with a carminative component – simethicone. It has a long-term antacid effect, has a mild laxative effect, successfully eliminates constipation and reduces flatulence in patients with stomach ulcers.

The dual mechanism of its action, combining acid-neutralizing ability and cytoprotective activity, provides protection of the gastric mucosa and its healing in case of damage.

Alkaline active components of the drug are finely dispersed, which increases their active surface, provides closer contact with the surface of the mucous membrane of the stomach and duodenum, slows down the evacuation of the contents of the stomach and lengthens the neutralizing effect.

Cytoprotective activity is associated with the activation of the synthesis of prostaglandins, which stimulate the secretion of mucus and bicarbonates from the gastric mucosa.

Given the ability of the drug to bind bile acids and lysolecithin, as well as to have a gastroprotective effect, Almagel Neo can be used to treat duodenogastric reflux.

Simethicone, which is part of the drug, helps to eliminate flatulence.

Simethicone is a stable silicone compound that is not absorbed from the digestive tract, causing the natural release of gases and their absorption by the intestinal walls.

Simethicone exerts its action in the lumen of the small intestine and is excreted unchanged from the body.

The constituents of the drug are not absorbed in the gastrointestinal tract and thus do not lead to clinically significant plasma concentrations when used at the recommended doses and for the recommended duration of treatment.

Aluminum hydroxide neutralizes the increased secretion of hydrochloric acid in the stomach, forming aluminum chloride. Under the influence of the alkaline environment of the intestine, the latter is converted into alkaline aluminum salts, which are poorly absorbed and excreted in the feces. With normal kidney function, the serum level of aluminum practically does not change.

Magnesium hydroxide also neutralizes hydrochloric acid in the stomach and turns into magnesium chloride. In the intestines, it turns into magnesium carbonate, which is poorly absorbed, so the concentration of magnesium ions in the blood practically does not change.

In patients with chronic renal failure, the level of aluminum and magnesium ions may increase to toxic values ​​due to a violation of their excretion.

Symptomatic treatment of diseases of the digestive tract, which are accompanied by increased or normal acidity of gastric juice and increased gas formation.

The drug is used alone or in combination with other drugs for:

• gastritis and duodenitis;
• stomach ulcer and duodenal ulcer;
• erosion of the stomach and duodenum;
• gastroesophageal reflux disease;
• duodenogastric reflux;
• functional dyspepsia;
• flatulence, discomfort as a result of increased gas formation.

Hypersensitivity to aluminum hydroxide, magnesium hydroxide or simethicone and / or excipients that make up Almagel NEO suspension. Severe renal dysfunction, including in patients on hemodialysis, in which there is a risk of increasing the concentration of aluminum and magnesium ions in the blood serum to toxic levels as a result of a decrease in excretion by the kidneys. Hypophosphatemia, severe osteoporosis, habitual constipation, chronic diarrhea, intestinal obstruction, suspected appendicitis, bleeding from the digestive tract of unknown origin, severe abdominal pain of unspecified origin, ulcerative colitis, conditions that cause water and electrolyte imbalance.