Description

Amaril (glimepiride) tablets 3 mg. №30

Ingredients

Active ingredient: Glimepiride 3 mg.
Other ingredients: Lactose monohydrate, microcrystalline cellulose, povidone, and magnesium stearate.

Dosage

Recommended dosage: The usual starting dose is 1 to 2 mg once daily. Dosage adjustments should be made based on blood glucose levels.

Indications

Amaril tablets are indicated for the treatment of type 2 diabetes mellitus when diet and exercise alone are not sufficient to control blood glucose levels.

Contraindications

Do not use Amaril tablets in patients with a history of hypersensitivity to glimepiride or other sulfonylureas.

Directions

Take Amaril tablets exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water.

Scientific Evidence

Studies have shown that glimepiride, the active ingredient in Amaril tablets, effectively lowers blood glucose levels by stimulating insulin release from pancreatic beta cells. Research has also demonstrated its role in reducing HbA1c levels, indicating improved long-term glycemic control.

Additional Information

It is important to monitor blood glucose levels regularly while taking Amaril tablets to ensure optimal control of diabetes. Consult your healthcare provider for personalized dosage recommendations and potential side effects.

Pharmacological Effects: Glimepiride works by binding to specific receptors on pancreatic beta cells, leading to an increase in insulin release. This helps lower blood glucose levels by facilitating the uptake of glucose into cells for energy production.

Clinical Trials: Clinical trials comparing glimepiride to other sulfonylureas have shown similar efficacy in lowering blood glucose levels. However, glimepiride may offer advantages in terms of reduced risk of hypoglycemia and once-daily dosing convenience.