Description
Amaril (Glimepiride) Tablets 4 mg. №30
Composition
Active Ingredient: Each tablet contains Glimepiride 4 mg.
Mechanism of Action
Glimepiride, a sulfonylurea, stimulates insulin release from pancreatic beta cells, leading to decreased blood glucose levels. It also enhances insulin sensitivity in peripheral tissues.
Pharmacological Properties
As a sulfonylurea, Glimepiride acts by binding to specific receptors on pancreatic beta cells, resulting in increased insulin secretion. This helps in regulating blood sugar levels by facilitating glucose uptake in tissues.
Indications for Use
Amaril tablets are prescribed for the management of type 2 diabetes mellitus in cases where lifestyle modifications alone are insufficient to control blood glucose levels effectively.
Contraindications
Amaril should not be administered to individuals with a known hypersensitivity to Glimepiride or other sulfonylureas. Patients with a history of severe hypoglycemia should also avoid its use.
Side Effects
Common side effects associated with Glimepiride include dizziness, headache, and nausea. It is advised to seek medical advice if these symptoms persist or worsen.
Usage Instructions
The typical initial dose of Amaril is 1 to 2 mg taken once daily. Dosage adjustments should be guided by blood glucose monitoring to achieve optimal glycemic control.
Benefits Compared to Analogues
Comparative studies have demonstrated that Glimepiride exhibits similar efficacy to other sulfonylureas in reducing blood glucose levels. Moreover, it carries a lower risk of hypoglycemia when compared to certain older sulfonylureas.
Suitable Patient Groups
Amaril is suitable for adult patients with type 2 diabetes mellitus who require pharmacological intervention to manage their condition. It is not recommended for children, pregnant individuals, or those with type 1 diabetes.
Storage and Shelf Life
Store Amaril tablets in a cool, dry place away from direct sunlight. Ensure the packaging is tightly closed. Check the expiration date on the packaging and do not use the product beyond that date.
Packaging Description
Amaril tablets are typically packaged in blister packs of 30 tablets each. The packaging should contain information on the dosage, active ingredients, and manufacturer details.
