Ambrolitin (ambroxol) syrup 15 mg/5 ml. 100 ml.

Ambrolitin (ambroxol) syrup 15 mg/5 ml. 100 ml.

$9.00

Manufacturer: Bulgaria

Drugs used for coughs and colds. mucolytic agents.

ATX code R05C B06.

Unless otherwise prescribed, the recommended dose of Ambrolitin®, syrup 15 mg/5 ml is:

children under 2 years of age: 2.5 ml 2 times a day (equivalent to 15 mg ambroxol hydrochloride per day);

children aged 2-6 years: 2.5 ml 3 times a day (equivalent to 22.5 mg ambroxol hydrochloride per day);

children aged 6-12 years: 5 ml 2-3 times a day (equivalent to 30-45 mg ambroxol hydrochloride per day);

adults and children over the age of 12 years: 10 ml 3 times a day (equivalent to 90 mg ambroxol hydrochloride per day) for the first 2-3 days and then 10 ml 2 times a day (equivalent to 60 mg ambroxol hydrochloride per day).

If necessary, the therapeutic effect for adults and children over the age of 12 years can be enhanced by increasing the dose to 20 ml 2 times a day (equivalent to 120 mg of ambroxol hydrochloride per day).

The drug can be used regardless of the meal.

Ambrolitin® should not be used for longer than 4-5 days without consulting a doctor.

In general, there are no restrictions on the duration of use, however, long-term therapy should be carried out under medical supervision.

Ambrolitin® does not contain alcohol.

 

Category:

Description

Ingredients

active ingredient : ambroxol;

5 ml of syrup contain ambroxol hydrochloride 15 mg;

excipients : sorbitol (E 420); citric acid, monohydrate; methyl parahydroxybenzoate (E 218); propyl parahydroxybenzoate (E 216); glycerol; propylene glycol; sodium saccharin; raspberry flavor; purified water.

Pharmacotherapeutic group

Drugs used for coughs and colds. mucolytic agents.

ATX code R05C B06.

Pharmacodynamics

The active substance of the drug – ambroxol – is an active metabolite of bromhexine, increases the secretion of the glands of the respiratory tract. Ambroxol enhances the release of pulmonary surfactant by direct action on type II pneumocytes in the alveoli and Clara cells in the bronchioles, and also stimulates ciliary activity. This leads to an increase in mucus secretion and excretion and to an improvement in mucociliary clearance. Improvement in mucociliary clearance has been proven during clinical and pharmacological studies.

Activation of fluid secretion and increased mucociliary clearance facilitate mucus clearance and reduce coughing.

The local anesthetic effect of ambroxol hydrochloride, which may be due to sodium channel blocking properties, was observed in a rabbit eye model. In vitro studies have shown that ambroxol hydrochloride blocks neuronal sodium channels; binding was reversible and concentration dependent.

Ambroxol hydrochloride has shown anti-inflammatory effects in vitro. Thus, ambroxol hydrochloride significantly reduces the release of cytokine from mononuclear and polymorphonuclear blood cells and tissues.

As a result of clinical trials involving patients with pharyngitis, a significant reduction in pain and redness in the throat was demonstrated when using the drug.

Due to the pharmacological properties of ambroxol, pain was quickly relieved in the treatment of diseases of the upper respiratory tract, which was observed during studies of the clinical efficacy of inhaled forms of ambroxol.

After the use of ambroxol hydrochloride, the concentrations of antibiotics (amoxicillin, cefuroxime, erythromycin) in bronchopulmonary secretion and sputum increase.

Indications

Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with impaired bronchial secretion and weakening of mucus movement.

Contraindications

Hypersensitivity to ambroxol or other components of the drug.

Directions

Unless otherwise prescribed, the recommended dose of Ambrolitin (ambroxol), syrup 15 mg/5 ml is:

children under 2 years of age: 2.5 ml 2 times a day (equivalent to 15 mg ambroxol hydrochloride per day);

children aged 2-6 years: 2.5 ml 3 times a day (equivalent to 22.5 mg ambroxol hydrochloride per day);

children aged 6-12 years: 5 ml 2-3 times a day (equivalent to 30-45 mg ambroxol hydrochloride per day);

adults and children over the age of 12 years: 10 ml 3 times a day (equivalent to 90 mg ambroxol hydrochloride per day) for the first 2-3 days and then 10 ml 2 times a day (equivalent to 60 mg ambroxol hydrochloride per day).

If necessary, the therapeutic effect for adults and children over the age of 12 years can be enhanced by increasing the dose to 20 ml 2 times a day (equivalent to 120 mg of ambroxol hydrochloride per day).

The drug can be used regardless of the meal.

Ambrolitin (ambroxol) should not be used for longer than 4-5 days without consulting a doctor.

In general, there are no restrictions on the duration of use, however, long-term therapy should be carried out under medical supervision.

Ambrolitin (ambroxol) does not contain alcohol.

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