Ambroxol (ambroxol hydrochloride) 30 syrup 30 mg/5 ml. 100 ml.

Ambroxol (ambroxol hydrochloride) 30 syrup 30 mg/5 ml. 100 ml.

$8.00

Manufacturer: Ukraine

Ambroxol increases the secretion of the glands of the respiratory tract, stimulates the activity of the villi of the respiratory tract, enhances the formation of surfactant in the lungs. These effects lead to easier mucus clearance and elimination (mucociliary clearance). Activation of fluid secretion and increased mucociliary clearance facilitate mucus clearance and reduce coughing.

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Description

Ingredients

active ingredient: ambroxol hydrochloride;

5 ml of syrup contains 30 mg of ambroxol hydrochloride (in terms of 100% dry matter);

excipients: benzoic acid (E 210), sucralose, hydroxyethyl cellulose, banana flavor, vanilla-cream flavor, purified water.

Pharmacotherapeutic group

Drugs used for coughs and colds. mucolytic agents. Ambroxol. ATX code R05C B06.

Pharmacodynamics

Ambroxol increases the secretion of the glands of the respiratory tract, stimulates the activity of the villi of the respiratory tract, enhances the formation of surfactant in the lungs. These effects lead to easier mucus clearance and elimination (mucociliary clearance). Activation of fluid secretion and increased mucociliary clearance facilitate mucus clearance and reduce coughing.

Pharmacokinetics

The effect of the drug occurs 30 minutes after its use and lasts approximately 10 hours.

Absorption of the drug is fast and fairly complete. Peak plasma levels are reached in 0.5-3 hours. The degree of binding of ambroxol to plasma proteins is 80-90%.

The distribution of ambroxol from the blood to the tissues is rapid, with a high concentration of the active substance in the lungs. The drug penetrates the blood-brain and placental barriers into breast milk.

Ambroxol is metabolized in the liver by conjugation. The plasma half-life is 10 hours; cumulation was not detected. In the form of water-soluble metabolites, approximately 90% is excreted by the kidneys, unchanged – 5%. The elimination half-life is prolonged in severe chronic renal failure.

Indications

Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with impaired bronchial secretion and weakening of sputum.

Contraindications

Hypersensitivity (allergy) to ambroxol or to other components of the drug.

Directions

Adults and children over 12 years old – 10 ml (2 dosing spoons) 2 times a day, which is equivalent to 120 mg of ambroxol hydrochloride per day.

Ambroxol syrup 30 mg/5 ml. can be taken with or without food. Eating does not affect the effectiveness of the drug.

The term for the treatment of acute respiratory diseases and the initial treatment of chronic conditions is up to 14 days. A doctor should be consulted if symptoms persist for more than 14 days or worsen despite taking the drug.

The highest dose regimen should be used for initial treatment, the dose can be halved after 14 days of drug treatment.

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