$7.00
Manufacturer: Germany
Drugs used for coughs and colds. mucolytic agents. ATX code R05C B06.
Ambroxol-Teva, syrup, is taken orally after meals. After taking it, it is recommended to drink 1 glass of water. The mucolytic effect of ambroxol is enhanced by the use of large amounts of liquid.
Adults and children over 12 years old: in the first 2-3 days – 10 ml 3 times a day (equivalent to 90 mg ambroxol hydrochloride per day), then – 10 ml 2 times a day (equivalent to 60 mg ambroxol hydrochloride per day). If necessary, the therapeutic effect for adults and children over 12 years of age can be enhanced by increasing the dose to 20 ml 2 times a day (equivalent to 120 mg of ambroxol hydrochloride per day).
For adults and children over 12 years of age, it is advisable to use a dosage form containing a high concentration of ambroxol hydrochloride (for example, Ambroxol-Teva, solution, 37.5 mg / 5 ml).
Description
Ingredients
active ingredient: ambroxol hydrochloride;
5 ml of syrup contain ambroxol hydrochloride 15 mg;
excipients: sorbitol solution, does not crystallize, propylene glycol, raspberry flavor, saccharin, purified water.
Pharmacotherapeutic group
Drugs used for coughs and colds. mucolytic agents. ATX code R05C B06.
Pharmacodynamics
Ambroxol hydrochloride increases the secretion of the glands of the respiratory tract. Ambroxol enhances the release of pulmonary surfactant by direct action on type II pneumocytes in the alveoli and Clara cells in the bronchioles, and also stimulates ciliary activity. This results in increased secretion and mucus secretion and improved mucociliary clearance.
Activation of fluid secretion and increased mucociliary clearance facilitate mucus clearance and reduce coughing.
A local anesthetic effect of ambroxol hydrochloride has been reported, which may be due to the ability to block sodium channels. In vitro studies have shown that ambroxol hydrochloride blocks neuronal sodium channels; binding was reversible and concentration dependent.
Ambroxol hydrochloride has been shown to be anti-inflammatory in vitro. In vitro studies have found that ambroxol hydrochloride significantly reduces cytokine release from the blood and tissue binding of mononuclear and polymorphonuclear cells.
A significant reduction in pain and redness in the throat in patients with pharyngitis was recorded when using the drug.
After the use of ambroxol hydrochloride, the concentration of antibiotics (amoxicillin, cefuroxime, erythromycin) in bronchopulmonary secretion and sputum increases.
Indications
Secretolytic therapy for acute and chronic broncho-pulmonary diseases associated with impaired bronchial secretion and weakening of mucus movement.
Contraindications
Hypersensitivity to ambroxol and / or other components of the drug.
Rare hereditary conditions through which incompatibility with the excipient of the drug is possible.
Directions
Ambroxol-Teva, syrup, is taken orally after meals. After taking it, it is recommended to drink 1 glass of water. The mucolytic effect of ambroxol is enhanced by the use of large amounts of liquid.
Adults and children over 12 years old: in the first 2-3 days – 10 ml 3 times a day (equivalent to 90 mg ambroxol hydrochloride per day), then – 10 ml 2 times a day (equivalent to 60 mg ambroxol hydrochloride per day). If necessary, the therapeutic effect for adults and children over 12 years of age can be enhanced by increasing the dose to 20 ml 2 times a day (equivalent to 120 mg of ambroxol hydrochloride per day).
For adults and children over 12 years of age, it is advisable to use a dosage form containing a high concentration of ambroxol hydrochloride (for example, Ambroxol-Teva, solution, 37.5 mg / 5 ml).
Children:
- at the age of 2 years (except for newborns and premature babies) – 2.5 ml 2 times a day (equivalent to 15 mg of ambroxol hydrochloride per day);
- at the age of 2 to 5 years – 2.5 ml 3 times a day (equivalent to 22.5 mg of ambroxol hydrochloride per day);
- at the age of 6 to 12 years – 5 ml 2-3 times a day (equivalent to 30-45 mg of ambroxol hydrochloride per day).
The duration of treatment depends on the characteristics of the course of the disease.
Ambroxol-Teva, syrup, should not be used for longer than 4-5 days without consulting a doctor.
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