Description

Amicacina (Amikacin) Sulfate Solution for Injections 250 mg/ml. 2 ml. Ampoules №1

Ingredients:

Amikacin sulfate, sodium citrate, sulfuric acid, and water for injection.

Dosage:

The usual adult dose is 15 mg/kg/day divided into 2 or 3 equal doses. Dosage adjustments may be needed based on renal function.

Indications:

Amicacina (Amikacin) Sulfate Solution for Injections is indicated for the treatment of serious infections caused by susceptible strains of bacteria.

Contraindications:

Do not use in patients with a known hypersensitivity to amikacin or any other aminoglycoside. Caution is advised in patients with pre-existing kidney problems.

Directions:

Administer by intramuscular or intravenous injection. Follow proper aseptic techniques during administration.

Scientific Evidence:

Amikacin, the active ingredient in Amicacina, is a broad-spectrum aminoglycoside antibiotic with potent bactericidal activity. Studies have shown its efficacy in treating severe bacterial infections, including those resistant to other antibiotics. Research published in the Journal of Antimicrobial Chemotherapy demonstrated the effectiveness of amikacin in combating multidrug-resistant Gram-negative bacteria.

Additional Information:

• Pharmacological Effects: Amikacin works by inhibiting bacterial protein synthesis, leading to cell death. It is particularly effective against aerobic, gram-negative bacteria.
• Clinical Trials: Clinical trials have shown that amikacin is well-tolerated and effective in treating various infections, including those caused by Pseudomonas aeruginosa and Acinetobacter species.