Amicitron forte (paracetamol) powder for oral solution 13g. sachet №10 without sugar

active ingredients: paracetamol, phenylephrine hydrochloride, pheniramine maleate, ascorbic acid;

1 sachet contains paracetamol 650 mg, phenylephrine hydrochloride 10 mg, pheniramine maleate 20 mg, ascorbic acid 50 mg;

excipients: isomalt (E 953), dye sunset yellow FCF (E 110), citric acid, sodium, acesulfame potassium, natural lemon flavor.

Analgesics. Other analgesics and antipyretics. Anilides. Paracetamol, combinations without psycholeptics.

ATX code N02B E51.

Amicitron forte (paracetamol) has an antipyretic, analgesic and mild anti-inflammatory effect. Paracetamol inhibits the synthesis of prostaglandins in the central nervous system (CNS) and blocks the conduction of pain impulses.

Phenylephrine – α-agonist, has a vasoconstrictive effect, reduces swelling of the nasal mucosa and paranasal sinuses.

Pheniramine – blocker of H1 receptors, reduces vascular permeability, eliminates lacrimation, itchy eyes and nose.

Ascorbic acid enhances the nonspecific resistance of the body.

Paracetamol is well absorbed from the gastrointestinal tract, crosses the placental barrier, passes into breast milk in small amounts, is metabolized in the liver by the cytochrome P450 system, excreted by the kidneys, the half-life is 1-4 hours. Duration of action – 3-4 hours.

Phenylephrine is metabolized in the intestine and liver, excreted by the kidneys.

Pheniramine is well absorbed from the gastrointestinal tract, metabolized in the liver by the cytochrome P450 system, the half-life is 16-18 hours, 70-83% is excreted by the kidneys.

Ascorbic acid is rapidly absorbed from the gastrointestinal tract, metabolized in the liver, and excreted by the kidneys.

Symptomatic treatment of acute respiratory infections and influenza: fever, headache, nasal congestion, runny nose, pain and aches in the muscles.