Aminoven 15pct solution for infusions 1000 ml. vial №1

Active substances:

L-isoleucine 5.2 g,

L-leucine 8.9 g,

L-lysine acetate 15.66 g (corresponds to the content of L-lysine 11.1 g),

L-methionine 3.8 g,

L-phenylalanine 5.5 g,

L-threonine 8.6 g,

L-tryptophan 1.6 g,

L-valine 5.5 g,

L-arginine 20 g,

L-histidine 7.3 g,

L-alanine 25 g,

glycine 18.5 g,

L-proline 17 g,

L-serine 9.6 g,

L-tyrosine 400 mg,

taurine 2 g;

Excipients: 

glacial acetic acid 4.45 g,

malic acid (to maintain the pH level) 4.9 – 6.1 g,

water for and up to 1 liter.

Aminoven 15% is intended for parenteral nutrition of patients with various pathologies with low, normal or increased protein requirements, when enteral nutrition is ineffective or impossible.

The interchangeable and irreplaceable L-amino acids contained in Aminoven are natural physiological components.

Like dietary amino acids derived from protein digestion, parenterally administered amino acids enter the total pool of free amino acids in the blood plasma and from there into cells for protein synthesis and into various metabolic pathways.

Complete or partial parenteral nutrition. Amino acid solutions are usually used in combination with sufficient energy sources (glucose, fat emulsions).

Prevention and therapy of protein losses when oral or enteral nutrition is not possible, insufficient or contraindicated.

• Violation of the metabolism of amino acids.
• metabolic acidosis.
• Renal failure in the absence of hemodialysis or hemofiltration.
• Severe liver failure.
• Liquid overload.
• Shock.
• Hypoxia.
• Decompensated heart failure.
• Newborn infants and children under 2 years old: adapted children’s amino acid preparations, the composition of which is specially designed to meet the metabolic needs of children, should be used (Aminoven Infant).
• It is not recommended to prescribe Aminoven 15% in children (under 18 years of age) due to the lack of sufficient clinical experience in this age group.

Aminoven 15% should only be administered into the central veins. The infusion can be continued for as long as the clinical condition of the patient requires, based on the daily requirement for amino acids.

Adults

Average daily dose: 6.7-13.3 ml of Aminoven 15% per kg of body weight (equivalent to 1.0-2.0 g of amino acids per kg of body weight), which corresponds to 470-930 ml of Aminoven 5% for a patient weighing 70 kg.

Maximum daily dose: 13.3 ml of Aminoven 15% per kg of body weight (equivalent to 2.0 g of amino acids per kg of body weight), which corresponds to 930 ml of Aminoven 15% for a patient weighing 70 kg.

Maximum infusion rate: 0.67 ml Aminoven 15% per kg of body weight per hour (equivalent to 0.1 g of amino acids per kg of body weight per hour).

Children: Aminoven 15% is not recommended for use in children (under 18 years of age).

Newborn infants and children under 2 years old: adapted children’s amino acid preparations, the composition of which is specially designed to meet the metabolic needs of children, should be used (Aminoven Infant).