Description

Amiokordin (amiodarone hydrochloride) tablets 200 mg. №60

Ingredients

Active ingredient: Amiodarone hydrochloride 200 mg per tablet.

Dosage

Recommended dosage: The usual maintenance dose is 200-400 mg daily, taken as a single dose or divided into two smaller doses.

Indications

Amiokordin tablets are indicated for the treatment of various types of serious irregular heartbeats (arrhythmias).

Contraindications

Do not use Amiokordin tablets if you are allergic to amiodarone or any other ingredients in the tablets. It is also contraindicated in patients with certain heart conditions.

Directions

Take Amiokordin tablets exactly as prescribed by your healthcare provider. Swallow the tablets whole with a full glass of water, and do not crush or chew them.

Scientific Evidence

Amiodarone has been extensively studied for its efficacy in managing various arrhythmias. Research published in the “Journal of the American College of Cardiology” has shown that amiodarone is effective in reducing the recurrence of atrial fibrillation and ventricular arrhythmias.

Additional Information

It is important to regularly monitor thyroid function, liver enzymes, and lung function while taking Amiokordin tablets. This medication may interact with other drugs, so inform your healthcare provider about all the medications you are taking.

Pharmacological Effects: Amiodarone works by prolonging the action potential duration and refractory period of cardiac tissues, thereby stabilizing the heart’s rhythm. It also has non-competitive alpha- and beta-adrenergic blocking effects, contributing to its antiarrhythmic properties.

Clinical Trials: Clinical trials have demonstrated the superior efficacy of amiodarone in managing ventricular arrhythmias compared to other antiarrhythmic agents. A study published in the “New England Journal of Medicine” showed a significant reduction in sudden cardiac death in patients treated with amiodarone.