Description

Amiokordin (Amiodarone Hydrochloride) Tablets 200 mg. №60

Composition

Active ingredient: Each tablet contains 200 mg of Amiodarone hydrochloride.

Mechanism of Action

Pharmacological Properties: Amiodarone prolongs the action potential duration and refractory period of cardiac tissues, stabilizing the heart’s rhythm. It also exhibits non-competitive alpha- and beta-adrenergic blocking effects, enhancing its antiarrhythmic properties.

Indications for Use

Indications: Amiokordin tablets are indicated for the treatment of various serious irregular heartbeats (arrhythmias).

Contraindications

Contraindications: Do not use Amiokordin tablets if you have a known allergy to amiodarone or any other tablet ingredients. It is contraindicated in patients with specific heart conditions.

Side Effects

Common side effects may include nausea, vomiting, fatigue, and visual disturbances. Serious side effects such as pulmonary toxicity and thyroid dysfunction may occur rarely.

Usage Instructions

Dosage: The usual maintenance dose ranges from 200-400 mg daily, administered as a single dose or divided into two smaller doses. Follow your healthcare provider’s instructions carefully.

Benefits Compared to Analogues

Amiokordin has demonstrated superior efficacy in managing ventricular arrhythmias compared to other antiarrhythmic agents. Clinical studies have shown a significant reduction in sudden cardiac death in patients treated with amiodarone.

Suitable Patient Groups

Amiokordin can be used in various patient populations, including adults, elderly individuals, and selected pediatric cases under close medical supervision.

Storage and Shelf Life

Store Amiokordin tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging, and do not use the tablets beyond the stated shelf life.

Packaging Description

Each package of Amiokordin contains 60 tablets of 200 mg strength. The tablets are typically packed in blister packs for easy and safe storage.

Scientific Evidence

Clinical studies have demonstrated the efficacy of amiodarone in managing various arrhythmias. Research published in reputable journals such as the “Journal of the American College of Cardiology” and the “New England Journal of Medicine” has highlighted the effectiveness of amiodarone in reducing the recurrence of atrial fibrillation and ventricular arrhythmias, as well as lowering the risk of sudden cardiac death.