Amixin (Tilorone) coated tablets 0.06 g №10

Amixin (Tilorone) coated tablets 0.06 g №10

$36.00

Manufacturer: Ukraine

Amixin (Tilorone) is an immunomodulatory and antiviral agent. Stimulates the formation of α, β, γ-interferons in the body. The main producers of interferon in response to drug administration are intestinal epithelial cells, hepatocytes, T-lymphocytes and granulocytes. After oral administration, the maximum production of interferon is determined in the sequence “intestine – liver – blood” after 4-24 hours. Stimulates bone marrow stem cells, depending on the dose enhances antibody formation, reduces the degree of immunosuppression, restores the ratio of T-suppressors / T-helpers. Effective against a wide range of viral infections, including influenza viruses, other acute respiratory viral infections, hepatitis A, B, C and herpes viruses.

In the course of animal studies (chicken and duck embryos), the high antiviral activity of the drug against the causative agent of highly pathogenic avian influenza (HPAI) of the H5N1 strain, as well as (in experiments on chickens) a significant immunostimulatory and adjuvant activity against antigens of the HPAI pathogen, was proved.

Category:

Description

Ingredients

active ingredient: thyrolon;

1 tablet contains tilorone 0.06 g (60 mg);

Excipients:

60 mg tablets: calcium hydrogen phosphate dihydrate, hypromellose (hydroxypropyl methylcellulose), microcrystalline cellulose, povidone, croscarmellose sodium, potato starch, polyethylene glycol (macrogol), talc, colloidal silicon dioxide, calcium stearate, titanium dioxide (E 171), candurin (titanium dioxide) (E 171), potassium aluminosilicate (E 555)), synthetic mixed red dye (hypromellose (hydroxypropyl methylcellulose), microcrystalline cellulose, titanium dioxide (E 171), Ponceau 4R lacquer dye (E 124), indigo lacquer dye (E 132), dye lacquer sunset yellow FCF (E 110));

Dosage form

Coated tablets.

Basic physical and chemical properties: tablets of a round shape with a biconvex surface, coated, dark pink (dosage 60 mg) colors, two layers are visible on the fracture.

Pharmacotherapeutic group

Immunostimulants. Other immunostimulants. ATX code L03A X.

Pharmacodynamics

Amixin (Tilorone) is an immunomodulatory and antiviral agent. Stimulates the formation of α, β, γ-interferons in the body. The main producers of interferon in response to drug administration are intestinal epithelial cells, hepatocytes, T-lymphocytes and granulocytes. After oral administration, the maximum production of interferon is determined in the sequence “intestine – liver – blood” after 4-24 hours. Stimulates bone marrow stem cells, depending on the dose enhances antibody formation, reduces the degree of immunosuppression, restores the ratio of T-suppressors / T-helpers. Effective against a wide range of viral infections, including influenza viruses, other acute respiratory viral infections, hepatitis A, B, C and herpes viruses.

In the course of animal studies (chicken and duck embryos), the high antiviral activity of the drug against the causative agent of highly pathogenic avian influenza (HPAI) of the H5N1 strain, as well as (in experiments on chickens) a significant immunostimulatory and adjuvant activity against antigens of the HPAI pathogen, was proved.

Indications

adults

Treatment and prevention of influenza and acute respiratory viral infections, treatment of viral hepatitis A, B, C, herpes infection, cytomegalovirus infection; as part of the complex therapy of infectious-allergic and viral encephalomyelitis (multiple sclerosis, leukoencephalitis, uveoencephalitis and meningoencephalitis), urogenital and respiratory chlamydia.

To reduce the degree of immunosuppression as part of the complex therapy of diseases accompanied by secondary induced immunodeficiencies (caused by exposure to x-rays, cytostatics, surgical interventions, etc.) and require immunocorrection.

Children aged 7 to 18

Treatment of influenza and acute respiratory viral infections.

Contraindications

Hypersensitivity to the active substance or to any of the components of Amixin (Tilorone). During pregnancy and breastfeeding. Age up to 7 years.

Directions

Amixin (Tilorone) is taken orally after a meal.

adults

In the treatment of influenza and acute respiratory viral infections : in the first 2 days of treatment – 125 mg, then – 125 mg after 48 hours. Heading dose – 750 mg.

For the prevention of influenza and acute respiratory viral infections: 125 mg once a week for 6 weeks.

Treatment of viral hepatitis A: on the 1st day of treatment – 125 mg of Amixin (Tilorone) 2 times, then – 125 mg every 48 hours. Heading dose – 1.25 g.

Prevention of viral hepatitis A: 125 mg once a week for 6 weeks.

Treatment of acute hepatitis B: in the first 2 days of treatment – 125 mg, then – 125 mg after 48 hours. Heading dose – 2 g. With a protracted course of the disease, the heading dose can be increased to 2.5 g.

In chronic hepatitis B : in the first 2 days of treatment – 250 mg, then – 125 mg after 48 hours. The course dose at the beginning of treatment is 2.5 g. Further, the drug is prescribed at a dose of 125 mg per week. In general, the course dose is 3.75 g to 5 g.

In acute hepatitis C: in the first 2 days of treatment – 125 mg, then – 125 mg after 48 hours. Heading dose – 2.5 g.

In chronic hepatitis C: in the first 2 days of treatment – 250 mg, then – 125 mg after 48 hours. The course dose at the beginning of treatment is 2.5 g. Further, the drug is prescribed at a dose of 125 mg per week. In general, the course dose is 5 g.

For the treatment of herpetic, cytomegalovirus infection: in the first 2 days of treatment – 125 mg, then – 125 mg after 48 hours. Heading dose – 2.5 g.

In the complex therapy of neuroviral infections – infectious-allergic and viral encephalomyelitis (multiple sclerosis, leukoencephalitis, uveoencephalitis and meningoencephalitis): in the first 2 days of treatment – 125 mg, then – 125 mg after 48 hours. Heading dose – from 1.5 to 1.75 g.

In the complex therapy of urogenital and respiratory chlamydia: in the first 2 days of treatment – 125 mg, then – 125 mg after 48 hours. Heading dose – 1.25 g.

To reduce the degree of immunosuppression as part of the complex therapy of diseases accompanied by secondary induced immunodeficiencies and require immunocorrection: 125-250 mg per week for 6 weeks. The maximum course dose is 1.5 g. Depending on the immunological parameters and the course of the disease, the course of treatment can be repeated with an interval between courses of 4 weeks.

Children aged 7 to 18

In uncomplicated forms of influenza or SARS: 60 mg 1 time per day on the 1st, 2nd, 4th day from the start of treatment. Heading dose – 180 mg.

In the event of complications of influenza or SARS: 60 mg 1 time per day on the 1st, 2nd, 4th and 6th day from the start of treatment. Heading dose – 240 mg.

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