Description

Amlessa (perindopril tert-butylamine) tablets 8 mg/10 mg. №30

Ingredients

Active ingredient: Perindopril tert-butylamine

Dosage

Recommended dosage: 1 tablet once daily

Indications

Indicated for: Hypertension, heart failure, post-myocardial infarction

Contraindications

Do not use if: History of angioedema related to previous ACE inhibitor therapy

Directions

– Take Amlessa tablets orally with or without food
– Swallow the tablet whole with a full glass of water

Scientific Evidence

Clinical studies have shown: Perindopril, the active ingredient in Amlessa, to be effective in reducing blood pressure and improving outcomes in patients with heart failure and post-myocardial infarction.

Additional Information

– Store at room temperature away from moisture and heat
– Keep out of reach of children

Pharmacological Effects: Perindopril is an ACE inhibitor that works by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This action results in vasodilation, reduced blood pressure, and improved cardiac function.

Clinical Trials: A study by Fox et al. (2003) demonstrated that perindopril significantly reduced the risk of cardiovascular events in patients with stable coronary artery disease. Another trial by Danchin et al. (2008) showed the benefits of perindopril in reducing mortality and hospitalizations in patients with heart failure.