Description

Amlessa (perindopril tert-butylamine) tablets 8 mg/5 mg. №30

Ingredients

Active ingredient: Perindopril tert-butylamine

Dosage

Recommended dosage: The usual dose is one tablet once a day, preferably taken in the morning before a meal.

Indications

Amlessa tablets are indicated for the treatment of hypertension and heart failure.

Contraindications

Do not use Amlessa tablets if you are pregnant or breastfeeding. Consult your doctor before use if you have a history of angioedema or kidney disease.

Directions

Take Amlessa tablets orally with a full glass of water. Follow the dosage instructions provided by your healthcare provider.

Scientific Evidence

Perindopril, the active ingredient in Amlessa tablets, is an ACE inhibitor that works by blocking the production of angiotensin II, a substance that narrows blood vessels and releases hormones that can raise blood pressure. Clinical trials have shown that ACE inhibitors like perindopril are effective in reducing blood pressure and improving outcomes in patients with heart failure.

Additional Information

It is important to regularly monitor your blood pressure while taking Amlessa tablets to ensure the medication is working effectively. Inform your doctor of any side effects or concerns. Avoid consuming alcohol while on this medication as it can further lower blood pressure.

Pharmacological studies have demonstrated that perindopril not only lowers blood pressure but also has cardioprotective effects by reducing the strain on the heart and improving its function. Research published in the Journal of Hypertension has shown that perindopril is effective in reducing cardiovascular events and mortality in patients with hypertension.

Clinical trials comparing perindopril with other ACE inhibitors have shown similar efficacy in lowering blood pressure and improving cardiac function. However, perindopril may have a better tolerability profile in some patients, making it a preferred choice for long-term treatment of hypertension and heart failure.