Description

Amlodipine-KRKA Tablets 10 mg. №30

Composition

Each tablet contains 10 mg of amlodipine besylate.

Mechanism of Action

Amlodipine, a calcium channel blocker, acts by relaxing the blood vessels, facilitating improved cardiac function and decreased blood pressure.

Pharmacological Properties

Amlodipine exerts its antihypertensive effects by inhibiting the influx of calcium ions into vascular smooth muscle cells, leading to vasodilation and reduced peripheral vascular resistance.

Indications for Use

Amlodipine is indicated for the management of hypertension and chronic stable angina.

Contraindications

Do not administer amlodipine to individuals with known hypersensitivity to amlodipine or other dihydropyridine calcium channel blockers.

Side Effects

• Hypotension
• Peripheral edema
• Dizziness
• Flushing

Usage Instructions

The typical dosage regimen involves the oral administration of one tablet once daily. It is recommended to seek individualized dosing guidance from a healthcare professional.

Benefits Compared to Analogues

Amlodipine has demonstrated superior efficacy in reducing both systolic and diastolic blood pressure levels compared to other calcium channel blockers.

Suitable Patient Groups

Amlodipine is suitable for adult patients, including the elderly, requiring antihypertensive therapy.

Storage and Shelf Life

Store amlodipine tablets in a cool, dry place away from direct sunlight. Check the packaging for the expiration date and do not use beyond that date.

Packaging Description

The product is supplied in a package containing 30 tablets of 10 mg strength each.

Clinical Evidence and Proven Effectiveness

Amlodipine has been extensively evaluated in clinical trials, consistently demonstrating its efficacy in reducing blood pressure and improving cardiovascular outcomes. Clinical studies have shown amlodipine to be effective in managing hypertension and angina.