Description

Amlodipine-TEVA Tablets 10 mg. №30

Ingredients:

Each tablet contains 10 mg of Amlodipine besylate.

Dosage:

The usual starting dose is 5 mg once daily with a maximum dose of 10 mg once daily.

Indications:

Amlodipine-TEVA is indicated for the treatment of hypertension and chronic stable angina.

Contraindications:

Do not use Amlodipine-TEVA if you are allergic to amlodipine or any other dihydropyridine calcium channel blockers.

Directions:

Take Amlodipine-TEVA exactly as prescribed by your healthcare provider. Swallow the tablet whole with water, with or without food.

Scientific Evidence:

Amlodipine, the active ingredient in Amlodipine-TEVA, is a long-acting calcium channel blocker that works by relaxing the blood vessels, making it easier for the heart to pump blood. Several studies have demonstrated the efficacy of amlodipine in lowering blood pressure and reducing the frequency of angina attacks.

Additional Information:

It is important to monitor blood pressure regularly while taking Amlodipine-TEVA. Some common side effects may include swelling in the ankles or feet, dizziness, and flushing. If you experience any severe side effects, contact your doctor immediately.

Pharmacological Effects:

Amlodipine-TEVA works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle. By blocking calcium channels, it causes vasodilation and reduces peripheral vascular resistance, leading to a decrease in blood pressure. Additionally, amlodipine dilates coronary arteries, improving blood flow to the heart muscle, which helps in the management of angina.

Clinical Trials and Comparative Effectiveness:

In a comparative study published in the Journal of Hypertension, amlodipine was found to be more effective in reducing blood pressure compared to other calcium channel blockers. The study also highlighted the long-term benefits of amlodipine in preventing cardiovascular events in hypertensive patients.