Description

Ampril (Ramipril) tablets 10 mg. №30

Ingredients:

Each tablet contains 10 mg of Ramipril.

Dosage:

The recommended dosage is one 10 mg tablet per day. It is important to follow the instructions of your healthcare provider.

Indications:

Ampril (Ramipril) tablets are indicated for the treatment of hypertension, heart failure, and to improve survival after a heart attack.

Contraindications:

Do not take Ampril (Ramipril) if you are pregnant, have a history of angioedema, or are allergic to Ramipril. Consult your doctor before starting this medication.

Directions:

Take Ampril (Ramipril) tablets orally with or without food, as directed by your healthcare provider. Swallow the tablet whole with a glass of water.

Scientific Evidence:

Ramipril, the active ingredient in Ampril tablets, is an ACE inhibitor that works by relaxing blood vessels, which helps to lower blood pressure and reduce the workload on the heart. Clinical trials have shown that Ramipril is effective in reducing the risk of cardiovascular events and improving outcomes in patients with heart failure.

Additional Information:

It is important to regularly monitor your blood pressure while taking Ampril (Ramipril) tablets. Inform your healthcare provider of any side effects or concerns. Avoid alcohol and potassium supplements while on this medication.

Pharmacological Effects:

Ramipril inhibits the angiotensin-converting enzyme (ACE), leading to decreased production of angiotensin II, a potent vasoconstrictor. By blocking this enzyme, Ramipril helps to dilate blood vessels, reduce blood pressure, and improve cardiac function. Additionally, it can prevent the progression of heart failure and reduce the risk of cardiovascular events.

Clinical Trials and Comparative Effectiveness:

Clinical studies have demonstrated the efficacy of Ramipril in reducing mortality and morbidity in patients with heart failure and post-myocardial infarction. Compared to other ACE inhibitors, Ramipril has shown similar effectiveness but with a lower incidence of side effects such as cough. Research has also indicated that Ramipril may have renoprotective effects in diabetic patients beyond its blood pressure-lowering properties.