Description

Ampril (Ramipril) tablets 2.5 mg. №30

Ingredients

Active ingredient: Ramipril 2.5 mg per tablet.

Dosage

Dosage: The usual dose of Ampril (Ramipril) is 2.5 mg once daily. Your doctor may adjust the dosage based on your condition.

Indications

Indications: Ampril (Ramipril) is indicated for the treatment of hypertension, heart failure, and to improve survival after a heart attack.

Contraindications

Contraindications: Do not use Ampril (Ramipril) if you are pregnant, have a history of angioedema related to previous ACE inhibitor therapy, or have severe kidney disease.

Directions

Directions: Take Ampril (Ramipril) tablets orally with or without food as directed by your doctor. Swallow the tablet whole with a glass of water.

Scientific Evidence

Ramipril, the active ingredient in Ampril tablets, is an ACE inhibitor that works by relaxing blood vessels, making it easier for the heart to pump blood. Studies have shown that ACE inhibitors like Ramipril are effective in reducing blood pressure and improving outcomes in patients with heart failure. Research published in the Journal of the American College of Cardiology demonstrated the benefits of Ramipril in reducing cardiovascular events in high-risk patients.

Additional Information

It is important to regularly monitor your blood pressure while taking Ampril (Ramipril) tablets. Inform your doctor if you experience any side effects such as dizziness, cough, or swelling of the face, lips, or throat. Avoid consuming alcohol while on this medication as it can further lower your blood pressure.

Pharmacological Effects

Ramipril inhibits the angiotensin-converting enzyme (ACE), which is involved in the production of angiotensin II, a potent vasoconstrictor. By blocking the effects of angiotensin II, Ramipril causes vasodilation, leading to a decrease in blood pressure. Additionally, Ramipril reduces the secretion of aldosterone, further contributing to its antihypertensive effects.

Clinical Trials and Comparative Effectiveness

Clinical trials have shown that Ramipril is effective in reducing the risk of cardiovascular events, such as heart attacks and strokes, in patients with high blood pressure and other cardiovascular risk factors. Compared to other ACE inhibitors, Ramipril has been found to have similar efficacy but may offer unique benefits in certain patient populations. Research comparing Ramipril to other antihypertensive medications like lisinopril and enalapril has shown comparable effectiveness in lowering blood pressure and improving cardiovascular outcomes.

Investigating the pharmacological actions and clinical outcomes of Ampril (Ramipril) tablets provides valuable insights into its role in managing cardiovascular conditions and improving patient outcomes.