Description

Andipal Forte (Metamizole Sodium) Tablets №100

Ingredients:

Each tablet contains:

• Metamizole Sodium
• Pitofenone Hydrochloride
• Bendazol Hydrochloride

Dosage:

Adults: Take 1-2 tablets 2-3 times a day. Do not exceed 6 tablets in 24 hours.

Indications:

Andipal Forte tablets are indicated for the relief of mild to moderate pain, including headache, toothache, neuralgia, and menstrual cramps.

Contraindications:

Do not use Andipal Forte tablets if you have a history of hypersensitivity to metamizole sodium or other ingredients in the product. Avoid use during pregnancy and breastfeeding.

Directions:

Swallow the tablets whole with a glass of water. Do not crush or chew the tablets. Consult a healthcare professional for prolonged use.

Scientific Evidence:

Metamizole sodium, the active ingredient in Andipal Forte tablets, is a non-opioid analgesic with antipyretic properties. It works by inhibiting the synthesis of prostaglandins, which are mediators of pain and inflammation in the body. Clinical studies have shown that metamizole sodium is effective in providing pain relief comparable to other commonly used analgesics.

Additional Information:

It is important to follow the recommended dosage and not exceed the maximum daily limit to avoid potential side effects. If you experience any adverse reactions, discontinue use and consult a healthcare provider. Keep out of reach of children and store in a cool, dry place.

Pharmacological Effects:

Metamizole sodium exerts its pharmacological effects by acting on the central nervous system to reduce pain perception and by inhibiting the production of inflammatory mediators. This dual mechanism of action makes it a potent analgesic and antipyretic agent. The combination with pitofenone hydrochloride and bendazol hydrochloride enhances the overall efficacy in providing relief from various types of pain.

Clinical Trials and Comparative Effectiveness:

A study published in the Journal of Pain Research compared the effectiveness of metamizole sodium with other analgesics in the management of postoperative pain. The results showed that metamizole sodium provided similar pain relief with a lower risk of adverse effects compared to opioids. This highlights the comparative effectiveness of Andipal Forte tablets in pain management.