$13.00
Manufacturer: Ukraine
Apply as a local agent for irrigation of the oral cavity and oropharynx.
Adults and children over 15 years old: 1 spray 4-6 times a day.
Children aged 6 to 15 years: 1 spray 2-3 times a day.
The course of treatment – no more than 5 days.
Description
Ingredients
active ingredients: hexetidine, choline salicylate, chlorobutanol hemihydrate;
1 ml of the drug contains hexetidine 1 mg choline salicylate 5 mg chlorbutanol hemihydrate in terms of chlorbutanol 2.5 mg;
excipients: sodium saccharin, polysorbate, propionic acid, ethanol 96%, lemon oil, anise oil, menthol, peppermint oil, eucalyptol, methyl salicylate, purified water.
Dosage form
Spray for the oral cavity.
Basic physical and chemical properties: transparent, slightly colored solution with a specific pleasant smell.
Pharmacotherapeutic group
Drugs used in diseases of the throat. Antiseptics. ATX code R02A A20.
Pharmacodynamics
The action of Angilex (hexetidine) is due to three active ingredients.
Antibacterial and antifungal activity. Hexetidine has an antibacterial effect on both gram-positive and gram-negative strains of microorganisms, both aerobic and anaerobic.
It should be noted that it has mainly a bacteriostatic effect on aerobic strains, the bactericidal effect is weak. On anaerobic strains, hexetidine has a pronounced bactericidal effect. The mechanism of action is a competitive interaction with thiamine: the structure of hexetidine is similar to the structure of thiamine, which is necessary for the growth of microorganisms.
Anti-inflammatory activity. Choline salicylate has analgesic, antipyretic and anti-inflammatory effects. For the treatment of diseases of the oral cavity.
The analgesic activity is provided by chlorobutanol. Use in otolaryngology (nose drops, rinses) and in dental practice (applications and irrigation) as an anesthetic.
Pharmacokinetics
Active substances are fixed on the oral mucosa, from where they are gradually released.
Indications
Antibacterial and analgesic for the local treatment of diseases of the oral mucosa and oropharynx.
Contraindications
Hypersensitivity to the components of Angilex (hexetidine). Contraindicated in patients with atrophic pharyngitis, bronchial asthma or any other respiratory disease associated with existing airway hypersensitivity.
Dosage and administration
Apply as a local agent for irrigation of the oral cavity and oropharynx.
Adults and children over 15 years old: 1 spray 4-6 times a day.
Children aged 6 to 15 years: 1 spray 2-3 times a day.
The course of treatment – no more than 5 days.
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