Description
Antimigren (Sumatriptan) Coated Tablets 50 mg. N3
Composition
Active ingredient: Sumatriptan succinate 50 mg per tablet.
Mechanism of Action
Sumatriptan, the active ingredient in Antimigren tablets, is a selective serotonin receptor agonist that works by narrowing blood vessels in the brain to relieve migraine headaches.
Pharmacological Properties
Sumatriptan is a 5-HT1 receptor subtype agonist that specifically targets the cranial blood vessels, leading to vasoconstriction and inhibition of pro-inflammatory neuropeptide release, thereby alleviating migraine symptoms.
Indications for Use
Antimigren (Sumatriptan) coated tablets are indicated for the acute treatment of migraine attacks with or without aura.
Contraindications
Do not use Antimigren (Sumatriptan) coated tablets if:
- You have uncontrolled hypertension.
- You have a history of coronary artery disease or coronary artery vasospasm.
- You have severe hepatic impairment.
Side Effects
Common side effects of Antimigren (Sumatriptan) tablets may include dizziness, drowsiness, chest tightness, and in rare cases, serious cardiovascular events. It is essential to consult a healthcare provider if any adverse reactions occur.
Usage Instructions
Dosage: The usual adult dose is 50 mg taken orally. If the migraine recurs after initial relief, a second dose may be taken after 2 hours, not exceeding 100 mg in a 24-hour period.
Directions for use: Swallow the tablet whole with water. Do not crush, chew, or break the tablet. It can be taken with or without food.
Benefits Compared to Analogues
Antimigren (Sumatriptan) tablets offer rapid relief from migraine symptoms due to the potent vasoconstrictive effects of sumatriptan, distinguishing it from other migraine medications.
Suitable Patient Groups
Antimigren (Sumatriptan) tablets are suitable for adult patients experiencing migraine attacks. Special caution is advised for patients with cardiovascular risk factors or hepatic impairment.
Storage and Shelf Life
Store Antimigren (Sumatriptan) tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the tablets beyond this date.
Packaging Description
The product is packaged in a box containing 3 blister packs of coated tablets, each pack holding 10 tablets.
Clinical Evidence and Proven Effectiveness
Sumatriptan has been extensively studied in clinical trials, demonstrating its efficacy in providing rapid relief from migraine pain, nausea, and sensitivity to light and sound. Patients treated with sumatriptan showed significant improvement compared to those receiving a placebo.
It is crucial to note that Antimigren (Sumatriptan) tablets are not intended for migraine prevention or the treatment of specific migraine subtypes. Patients with a history of cardiovascular disease should consult their healthcare provider before using this medication.
